Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-Y-JAK1 [cytosol]
Stable Identifier
R-DME-451921
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q24592
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by CSF3 (G-CSF) (Drosophila melanogaster)
Inactivation of CSF3 (G-CSF) signaling (Drosophila melanogaster)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Drosophila melanogaster)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Drosophila melanogaster)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Drosophila melanogaster)
CSF3 dimer:K48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Drosophila melanogaster)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Drosophila melanogaster)
phospho-p-Y-JAK1 [cytosol] (Drosophila melanogaster)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Drosophila melanogaster)
phospho-p-Y-JAK1 [cytosol] (Drosophila melanogaster)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [lysosomal membrane] (Drosophila melanogaster)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Drosophila melanogaster)
CSF3 dimer:K48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Drosophila melanogaster)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Drosophila melanogaster)
phospho-p-Y-JAK1 [cytosol] (Drosophila melanogaster)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Drosophila melanogaster)
phospho-p-Y-JAK1 [cytosol] (Drosophila melanogaster)
p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Drosophila melanogaster)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-SHC1:GRB2:p-Y643-GAB2:p-Y546,Y584-PTPN11 [plasma membrane] (Drosophila melanogaster)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Drosophila melanogaster)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 [plasma membrane] (Drosophila melanogaster)
CSF3 dimer:p-4Y-CSF3R:LYN:p-Y-JAK1 [plasma membrane] (Drosophila melanogaster)
p-4Y-CSF3R:LYN:p-Y-JAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-Y-JAK1 [cytosol] (Drosophila melanogaster)
p-4Y-CSF3R:LYN:p-Y-JAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-Y-JAK1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24592 hop
Gene Names
hop, HD-160, CG1594
Chain
chain:1-1177
Reference Genes
BioGPS Gene:32080 hop
CTD Gene:32080 hop
KEGG:dme:Dmel_CG1594 hop
Monarch:32080 hop
NCBI Gene:32080 hop
UCSC:Q24592 hop
Reference Transcript
RefSeq:NM_078564.3 hop
Other Identifiers
153404_at
1639072_at
32080
GO:0001745
GO:0001751
GO:0002009
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005126
GO:0005524
GO:0005829
GO:0005856
GO:0006468
GO:0007163
GO:0007259
GO:0007260
GO:0007298
GO:0007350
GO:0007365
GO:0007399
GO:0007424
GO:0007442
GO:0007455
GO:0007472
GO:0007478
GO:0007481
GO:0007538
GO:0007616
GO:0009887
GO:0009898
GO:0012505
GO:0016020
GO:0016318
GO:0016476
GO:0016740
GO:0019100
GO:0019221
GO:0019827
GO:0022414
GO:0030154
GO:0030182
GO:0030707
GO:0030713
GO:0031453
GO:0035167
GO:0035206
GO:0035556
GO:0038083
GO:0038127
GO:0042067
GO:0042386
GO:0043226
GO:0045317
GO:0045475
GO:0048749
GO:0048856
GO:0048870
GO:0050877
GO:0051607
GO:0060031
GO:0065008
GO:0071907
GO:0071944
GO:0098542
GO:0140096
Participates
as a component of
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [lysosomal membrane] (Drosophila melanogaster)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Drosophila melanogaster)
p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Drosophila melanogaster)
p-4Y-CSF3R:LYN:p-Y-JAK1 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
HOP [cytosol]
Phospho HOP [cytosol]
phospho-p-JAK2 [cytosol]
phospho-p-Y813-JAK2 [cytosol]
phospho-p-TYK2 [cytosol]
TYK2 [cytosol]
phospho-p-12Y-JAK2 [cytosol]
phospho-p-Y1007-JAK2 [cytosol]
JAK1 [cytosol]
JAK3 [cytosol]
JAK2 [cytosol]
Inferred From
p-Y-JAK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_511119.2
ENSEMBL
FBtr0073457
,
FBpp0073313
FlyBase
FBgn0004864
PRO
Q24592
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text