LFT binds to FT and DS

Stable Identifier
R-DME-451846
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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LFT binds to FT and DS
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The small protein Lowfat (LFT) binds to the cytoplasmic domains of the cadherin domain containing transmembrane proteins Fat (FT) and Dachsous (DS). The function of LFT is currently unknown but it does appear to increase FT and DS protein levels.
Literature References
PubMed ID Title Journal Year
19710173 Drosophila lowfat, a novel modulator of Fat signaling

Kucuk, B, Irvine, KD, Mao, Y

Development 2009
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Input
Output
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Authored
Williams, MG  (2010-01-14)
Reviewed
Irvine, KD  (2009-11-25)
Created
Williams, MG  (2010-01-14)
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