DCO binds to FT

Stable Identifier
R-DME-451839
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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DCO binds to FT
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Fat (FT) is cleaved in its extracellular domain at an unknown site with the two fragments produced remaining stably associated after processing. The casein kinase 1 epsilon orthologue, Discs overgrown (DCO) binds to the cytoplasmic part of FT.
Literature References
PubMed ID Title Journal Year
19574458 Processing and phosphorylation of the Fat receptor

Feng, Y, Irvine, KD

Proc Natl Acad Sci U S A 2009
19540118 Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown

Clayton, L, Arbouzova, NI, Saburi, S, Varelas, X, Silva, E, Wrana, J, Sopko, R, Barrios-Rodiles, M, Shaw, S, Gardano, L, Matakatsu, H, Blair, S, McNeill, H

Curr Biol 2009
Participants
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Authored
Williams, MG  (2010-01-14)
Reviewed
Irvine, KD  (2009-11-25)
Created
Williams, MG  (2010-01-14)
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