Reactome | Ekar [plasma membrane]

Ekar [plasma membrane]

Stable Identifier

R-DME-451322-4

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

Edited GRIK 1 (GluR5), Q0KIF2

Locations in the PathwayBrowser

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Neuronal System (Drosophila melanogaster)

- Transmission across Chemical Synapses (Drosophila melanogaster)
  - Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
    - Activation of kainate receptors upon glutamate binding (Drosophila melanogaster)
      - Ionotropic activity of kainate receptors (Drosophila melanogaster)
        
        Activation of Na-permeable kainate receptors (Drosophila melanogaster)
        
        Activation of Edited Kainate receptors (Drosophila melanogaster)
        
        Edited Kainate Receptor-glutamate complex [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate receptors [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 and GRIK2 heteroteramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
        
        Ekar [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 homomer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
        
        Ekar [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate Receptor binds glutamate (Drosophila melanogaster)
        
        Edited Kainate Receptor-glutamate complex [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate receptors [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 and GRIK2 heteroteramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
        
        Ekar [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 homomer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
        
        Ekar [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate receptors [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 and GRIK2 heteroteramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
        
        Ekar [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 homomer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
        
        Ekar [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q0KIF2

Gene Names

Ekar

Reference Genes

BioGPS Gene:43806 Ekar

ENSEMBL:FBgn0039916

FlyBase:FBgn0039916

KEGG:dme:Dmel_CG9935 Ekar

Monarch:43806 Ekar

NCBI Gene:43806 Ekar

UCSC:Q0KIF2 Ekar

Reference Transcript

RefSeq:NM_001042785.2 Ekar

Other Identifiers

150985_at

1626574_at

43806

GO:0005216

GO:0005886

GO:0006811

GO:0015276

GO:0015277

GO:0016020

GO:0016057

GO:0034220

GO:0035235

GO:0035249

GO:0038023

GO:0045202

GO:0045211

GO:0055085

GO:0060025

GO:0071484

GO:0071632

GO:0098839

Participates

as a member of

Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

Ekar [plasma membrane]

Inferred From

Edited GRIK 1 (GluR5) [plasma membrane] (Homo sapiens)

Modified Residues

Name

L-glutamine 636 replaced with L-arginine (in Homo sapiens)

Coordinate

636

PsiMod

L-glutamine removal [MOD:01637]

A protein modification that effectively removes or replaces an L-glutamine.

L-arginine residue [MOD:00011]

A protein modification that effectively converts a source amino acid residue to an L-arginine.

Cross References

RefSeq

NP_001036250.1

ENSEMBL

FBgn0039916, FBtr0110906, FBpp0110206

FlyBase

FBgn0039916