Reactome | GluRIIE [plasma membrane]

GluRIIE [plasma membrane]

Stable Identifier

R-DME-451318-3

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

Edited GRIK2 (GluR6), Q0KI42

Locations in the PathwayBrowser

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Neuronal System (Drosophila melanogaster)

- Transmission across Chemical Synapses (Drosophila melanogaster)
  - Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
    - Activation of kainate receptors upon glutamate binding (Drosophila melanogaster)
      - Ionotropic activity of kainate receptors (Drosophila melanogaster)
        
        Activation of Na-permeable kainate receptors (Drosophila melanogaster)
        
        Activation of Edited Kainate receptors (Drosophila melanogaster)
        
        Edited Kainate Receptor-glutamate complex [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate receptors [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 and GRIK2 heteroteramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)
        
        GluRIIE [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK2 homomer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)
        
        GluRIIE [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate Receptor binds glutamate (Drosophila melanogaster)
        
        Edited Kainate Receptor-glutamate complex [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate receptors [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 and GRIK2 heteroteramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)
        
        GluRIIE [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK2 homomer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)
        
        GluRIIE [plasma membrane] (Drosophila melanogaster)
        
        Edited Kainate receptors [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK1 and GRIK2 heteroteramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)
        
        GluRIIE [plasma membrane] (Drosophila melanogaster)
        
        Edited GRIK2 homomer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)
        
        GluRIIE [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q0KI42

Gene Names

GluRIIE

Reference Genes

BioGPS Gene:318623 GluRIIE

ENSEMBL:FBgn0051201

Flybase:FBgn0051201

KEGG Gene (Drosophila melanogaster):Dmel_CG31201 GluRIIE

Monarch:318623 GluRIIE

NCBI Gene:318623 GluRIIE

UCSC:Q0KI42 GluRIIE

Reference Transcript

RefSeq:NM_001043268.2 GluRIIE

Other Identifiers

1638780_at

318623

GO:0004970

GO:0005215

GO:0005216

GO:0005886

GO:0006811

GO:0006816

GO:0007154

GO:0007274

GO:0008066

GO:0008328

GO:0015276

GO:0016020

GO:0019722

GO:0022849

GO:0023052

GO:0034220

GO:0035235

GO:0035249

GO:0038023

GO:0043226

GO:0045202

GO:0045211

GO:0050804

GO:0055085

GO:0060025

GO:0060078

GO:0060089

GO:0097482

GO:0098839

GO:1904315

Participates

as a member of

Homologues of Edited GRIK2 (GluR6) [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

GluRIIE [plasma membrane]

Inferred From

Edited GRIK2 (GluR6) [plasma membrane] (Homo sapiens)

Modified Residues

Name

L-glutamine 621 replaced with L-arginine (in Homo sapiens)

Coordinate

621

PsiMod

L-glutamine removal [MOD:01637]

A protein modification that effectively removes or replaces an L-glutamine.

L-arginine residue [MOD:00011]

A protein modification that effectively converts a source amino acid residue to an L-arginine.

Name

3-(S-L-cysteinyl)-L-tyrosine at 571 (in Homo sapiens)

Coordinate

571

PsiMod Name

3-(S-L-cysteinyl)-L-tyrosine [MOD:00803]

PsiMod Definition

A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 3-(S-L-cysteinyl)-L-tyrosine.

Name

L-isoleucine 567 replaced with L-valine (in Homo sapiens)

Coordinate

567

PsiMod

L-valine residue [MOD:00029]

A protein modification that effectively converts a source amino acid residue to an L-valine.

L-isoleucine removal [MOD:01640]

A protein modification that effectively removes or replaces an L-isoleucine.

Cross References

RefSeq

NP_001036733.1

Flybase

FBgn0051201

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