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CDC42 [cytosol]
Stable Identifier
R-DME-442630
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P40793
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Activation of Cdc42 (Drosophila melanogaster)
CDC42:GDP [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Factors involved in megakaryocyte development and platelet production (Drosophila melanogaster)
DOCKs bind to RhoGEFs (Drosophila melanogaster)
DOCK-GEFs:RAC1, CDC42 [cytosol] (Drosophila melanogaster)
RAC1, CDC42 [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC1, CDC42 [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)
VAV1 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
VAV1 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
VAV1 Rho/Rac effectors:GTP [cytosol] (Drosophila melanogaster)
VAV1 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
VAV2 is a GEF for Rho/Rac family kinases (Drosophila melanogaster)
VAV2 Rho/Rac effectors:GDP [cytosol] (Drosophila melanogaster)
VAV2 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
VAV2 Rho/Rac effectors:GTP [cytosol] (Drosophila melanogaster)
VAV2 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
CDC42 GTPase cycle (Drosophila melanogaster)
CDC42 GDIs block activation of CDC42 (Drosophila melanogaster)
CDC42:GDP:CDC42 GDIs [cytosol] (Drosophila melanogaster)
CDC42:GDP [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC1:GTP:RAC1 effectors [plasma membrane] (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC2 GTPase cycle (Drosophila melanogaster)
RAC2 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC3 GTPase cycle (Drosophila melanogaster)
RAC3 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
RAC3:GTP:RAC3 effectors [plasma membrane] (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
CDC42 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P40793
Reference Genes
BioGPS Gene:32981
ENSEMBL:FBgn0010341
FlyBase:FBgn0010341
KEGG:dme:Dmel_CG12530
Monarch:32981
NCBI Gene:32981
UCSC:P40793
Reference Transcript
RefSeq:NM_078690.4
RefSeq:NM_001258833.3
RefSeq:NM_001258834.3
Other Identifiers
143599_at
1633543_s_at
32981
GO:0001667
GO:0002376
GO:0003006
GO:0003014
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005634
GO:0005737
GO:0005886
GO:0005912
GO:0005938
GO:0006897
GO:0006909
GO:0007010
GO:0007015
GO:0007163
GO:0007264
GO:0007266
GO:0007274
GO:0007286
GO:0007298
GO:0007349
GO:0007391
GO:0007409
GO:0007411
GO:0008045
GO:0008360
GO:0008582
GO:0009611
GO:0009653
GO:0010592
GO:0016028
GO:0016192
GO:0016318
GO:0016787
GO:0019901
GO:0022412
GO:0022414
GO:0023052
GO:0030011
GO:0030027
GO:0030030
GO:0030031
GO:0030036
GO:0030041
GO:0030424
GO:0030426
GO:0030707
GO:0030833
GO:0030866
GO:0031175
GO:0031532
GO:0032488
GO:0032794
GO:0035006
GO:0035010
GO:0035011
GO:0035099
GO:0035147
GO:0035318
GO:0042060
GO:0043226
GO:0043227
GO:0045177
GO:0045185
GO:0045200
GO:0045202
GO:0045860
GO:0046330
GO:0046843
GO:0046928
GO:0048010
GO:0048477
GO:0048675
GO:0048812
GO:0048813
GO:0048856
GO:0048870
GO:0050770
GO:0050877
GO:0050975
GO:0051130
GO:0051491
GO:0051601
GO:0060429
GO:0060446
GO:0065003
GO:0070161
GO:0071944
GO:0072659
GO:0090303
GO:0097206
GO:0098542
GO:0098772
Participates
as a candidate of
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
VAV1 effectors [cytosol] (Drosophila melanogaster)
VAV2 effectors [cytosol] (Drosophila melanogaster)
as a member of
RAC1, CDC42 [cytosol] (Drosophila melanogaster)
as a component of
CDC42:GDP [cytosol] (Drosophila melanogaster)
CDC42:GTP [cytosol] (Drosophila melanogaster)
Other forms of this molecule
RHOJ [plasma membrane]
RHOQ [plasma membrane]
RHOQ [Golgi-associated vesicle membrane]
CDC42 [endoplasmic reticulum membrane]
CDC42 [plasma membrane]
Inferred From
CDC42 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
FBpp0301154
,
FBpp0301153
,
FBpp0074520
,
FBtr0074751
,
FBtr0309214
,
FBtr0309215
,
FBgn0010341
FlyBase
FBgn0010341
PRO
P40793
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O97111
4
par-6 [cytosol]
(R-DME-419967)
par-6 [cytosol]
(R-DME-419973)
par-6 [cytosol]
(R-DME-420001)
phospho-par-6 [plasma membrane]
(R-DME-2134533)
0.713
5
UniProt:Q9VXE5
4
PAK7 [plasma membrane]
(R-DME-211555)
PAK5 [cytosol]
(R-DME-428459)
PAK4 [cytosol]
(R-DME-428461)
PAK6 [cytosol]
(R-DME-428454)
0.524
2
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