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UbcE2M [cytosol]
Stable Identifier
R-DME-4419894
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
G76-NEDD8-C111-AcM-UBE2M, Q9VSF3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Neddylation (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
Transfer of NEDD8 to AcM-UBE2M (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
TGF-beta receptor signaling activates SMADs (Drosophila melanogaster)
CBL neddylates TGFBR2 (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
UbcE2M [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VSF3
Gene Names
UbcE2M
Reference Genes
BioGPS Gene:38916 UbcE2M
ENSEMBL:FBgn0035853
Flybase:FBgn0035853
KEGG Gene (Drosophila melanogaster):Dmel_CG7375 UbcE2M
Monarch:38916 UbcE2M
NCBI Gene:38916 UbcE2M
UCSC:Q9VSF3 UbcE2M
Reference Transcript
RefSeq:NM_001274638.1 UbcE2M
RefSeq:NM_001274639.1 UbcE2M
RefSeq:NM_139930.2 UbcE2M
Other Identifiers
154483_at
1630816_at
38916
GO:0000166
GO:0002376
GO:0003824
GO:0005524
GO:0005575
GO:0005634
GO:0016740
GO:0019788
GO:0023052
GO:0036211
GO:0043226
GO:0045116
GO:0045879
GO:0061059
GO:0061654
GO:0098542
GO:0140096
Participates
as a component of
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Other forms of this molecule
UbcE2M [nucleoplasm]
UbcE2M [nucleoplasm]
UbcE2M [cytosol]
UbcE2M [cytosol]
Inferred From
G76-NEDD8-C111-AcM-UBE2M [cytosol]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 111 and 76 (in Homo sapiens)
Coordinate
111
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Name
N-acetyl-L-methionine at 1 (in Homo sapiens)
Coordinate
1
PsiMod Name
N-acetyl-L-methionine [MOD:00058]
PsiMod Definition
A protein modification that effectively converts an L-methionine to N-acetyl-L-methionine.
Cross References
RefSeq
NP_001261568.1
,
NP_001261567.1
,
NP_648187.1
Flybase
FBgn0035853
IntEnz
2.3.2.34
PRO
Q9VSF3
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9W5E1 Roc1a
3
ROC1A [cytosol]
(R-DME-205902)
RBX1 [nucleoplasm]
(R-DME-1234142)
RBX1 [cytosol]
(R-DME-180582)
0.488
2
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