Calcium influx via CRAC

Stable Identifier
R-DME-434802
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Calcium influx via CRAC

Activation of Calcium-release-activated (CRAC) channels allows influx of calcium. The Orai component of CRAC is responsible for the selectivity of the channel, while the Stim component is responsible for activation.

Literature References
PubMed ID Title Journal Year
16921385 Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

Jiang, W, Zhang, SL, Yu, Y, Safrina, O, Cahalan, MD, Yeromin, AV

Nature 2006
Participants
Catalyst Activity

store-operated calcium channel activity of CRAC channel [plasma membrane]

Orthologous Events
Authored
Reviewed
Created
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