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Sirt1 [nucleoplasm]
Stable Identifier
R-DME-427531
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
SIRT1, Q9VK34
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
MITF-M-regulated melanocyte development (Drosophila melanogaster)
Transcriptional and post-translational regulation of MITF-M expression and activity (Drosophila melanogaster)
HINT1 binds MITF-M (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
SIRT1 deacetylates HINT1 dimer (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
Epigenetic regulation of gene expression (Drosophila melanogaster)
Epigenetic regulation by WDR5-containing histone modifying complexes (Drosophila melanogaster)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Drosophila melanogaster)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Drosophila melanogaster)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Drosophila melanogaster)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
Negative epigenetic regulation of rRNA expression (Drosophila melanogaster)
SIRT1 negatively regulates rRNA expression (Drosophila melanogaster)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
eNoSC [nucleoplasm] (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
eNoSC deacetylates histone H3 (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
eNoSC [nucleoplasm] (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
eNoSC dimethylates histone H3 at lysine-9 (Drosophila melanogaster)
eNoSC [nucleoplasm] (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
FOXO-mediated transcription (Drosophila melanogaster)
Regulation of FOXO transcriptional activity by acetylation (Drosophila melanogaster)
SIRT1,SIRT3 deacetylate FOXO3 (Drosophila melanogaster)
Sirt1 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VK34
Gene Names
Sirt1
Reference Genes
BioGPS Gene:34708 Sirt1
ENSEMBL:FBgn0024291
FlyBase:FBgn0024291
KEGG:dme:Dmel_CG5216 Sirt1
Monarch:34708 Sirt1
NCBI Gene:34708 Sirt1
UCSC:Q9VK34 Sirt1
Reference Transcript
RefSeq:NM_058003.4 Sirt1
Other Identifiers
153597_at
1628368_at
34708
GO:0001223
GO:0002039
GO:0003714
GO:0003824
GO:0004407
GO:0005634
GO:0005637
GO:0005654
GO:0005694
GO:0005737
GO:0006325
GO:0006355
GO:0008340
GO:0016740
GO:0016787
GO:0017136
GO:0023052
GO:0031507
GO:0032041
GO:0032869
GO:0033553
GO:0033558
GO:0034979
GO:0042981
GO:0043226
GO:0045747
GO:0045892
GO:0046331
GO:0046872
GO:0046969
GO:0046970
GO:0048149
GO:0060090
GO:0070403
GO:0097372
GO:0140096
GO:0140110
GO:0140765
GO:0141051
GO:0141222
GO:1901416
GO:2000253
Participates
as an input of
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Drosophila melanogaster)
as a component of
eNoSC [nucleoplasm] (Drosophila melanogaster)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Drosophila melanogaster)
This entity regulates
Positively
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci
(Drosophila melanogaster)
HINT1 binds MITF-M
(Drosophila melanogaster)
Inferred From
SIRT1,SIRT3 [nucleoplasm]
(Homo sapiens)
SIRT1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_477351.1
ENSEMBL
FBtr0080434
,
FBpp0080015
,
FBgn0024291
FlyBase
FBgn0024291
PRO
Q9VK34
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