Reactome | TyrRII [plasma membrane]

TyrRII [plasma membrane]

Stable Identifier

R-DME-390669-3

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

ADRA1A, Q9VEG2

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by GPCR (Drosophila melanogaster)
  - GPCR downstream signalling (Drosophila melanogaster)
    - G alpha (12/13) signalling events (Drosophila melanogaster)
      - Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
      - Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
      - The Ligand:GPCR:G12/13 complex dissociates (Drosophila melanogaster)
        
        GPCRs that activate G12/13 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
    - G alpha (q) signalling events (Drosophila melanogaster)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
      - The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
        
        GPCRs that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
  - GPCR ligand binding (Drosophila melanogaster)
    - Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
      - Amine ligand-binding receptors (Drosophila melanogaster)
        
        Adrenoceptors (Drosophila melanogaster)
        
        ADRA1A,B,D bind ADR,NAd (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D:ADR,NAd [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        α1-agonists:ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        α1-antagonists:ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        α1-agonists bind ADRA1A,B,D (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        α1-agonists:ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        α1-antagonists bind ADRA1A,B,D (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)
        
        α1-antagonists:ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        ADRA1A,B,D [plasma membrane] (Drosophila melanogaster)
        
        Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)
        
        TyrRII [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VEG2

Gene Names

TyrRII

Reference Genes

BioGPS Gene:42135 TyrRII

ENSEMBL:FBgn0038541

Flybase:FBgn0038541

KEGG Gene (Drosophila melanogaster):Dmel_CG16766 TyrRII

Monarch:42135 TyrRII

NCBI Gene:42135 TyrRII

UCSC:Q9VEG2 TyrRII

Reference Transcript

Other Identifiers

150096_at

1623168_at

42135

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007193

GO:0008226

GO:0008227

GO:0016020

GO:0023052

GO:0060089

GO:0071418

GO:0071880

GO:0071928

Participates

as a member of

Homologues of ADRA1A [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

TyrRII [plasma membrane]

Inferred From

ADRA1A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001287380.1, NP_001262683.1, NP_001262682.1, NP_650651.1

Flybase

FBgn0038541

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