D inhibits WTS

Stable Identifier
R-DME-390141
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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D inhibits WTS
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In the absence of the transmembrane cadherin Fat (FT), the unconventional myosin Dachs (D) accumulates at the plasma membrane where it has access to and inhibits Warts (WTS) kinase.
Literature References
PubMed ID Title Journal Year
16980976 Delineation of a Fat tumor suppressor pathway

Fehon, R, Irvine, KD, Maitra, S, Rauskolb, C, Feng, Y, Cho, E

Nat Genet 2006
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Output
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Authored
Williams, MG  (2009-01-23)
Reviewed
Irvine, KD  (2009-11-25)
Created
Williams, MG  (2009-01-23)
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