DSH binds to DAAM

Stable Identifier
R-DME-350396
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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DSH binds to DAAM
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Dishevelled Associated Activator of Morphogenesis (DAAM) is autoinhibited by intramolecular interactions between its GBD and DAD domains. Dishevelled (DSH) binds to the DAD domain of DAAM and disrupts the autoinhibitory interaction, thus activating DAAM.
Literature References
PubMed ID Title Journal Year
16469972 The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton

Djiane, A, Matusek, T, Mihaly, J, Brunner, D, Mlodzik, M, Jankovics, F

Development 2006
Participants
Input
Output
Participates
as an event of
Inferred From
Dvl2 binds to Daam1 (Homo sapiens)
Authored
Williams, MG  (2008-05-20)
Reviewed
Axelrod, JD  (2009-11-19)
Created
Williams, MG  (2008-05-19)
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