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Go!
gig [cytosol]
Stable Identifier
R-DME-2980548
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
TSC2, Q9VW83
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
Formation of TSC1:TSC2 complex (Drosophila melanogaster)
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT phosphorylates targets in the cytosol (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
Inhibition of TSC complex formation by PKB (Drosophila melanogaster)
Phosphorylation of TSC2 by PKB (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
Phosphorylation of complexed TSC2 by PKB (Drosophila melanogaster)
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Rab regulation of trafficking (Drosophila melanogaster)
TBC/RABGAPs (Drosophila melanogaster)
TBC1D7 binds the TSC1-TSC2 complex (Drosophila melanogaster)
TBC1D7:TSC1:TSC2 [cytosol] (Drosophila melanogaster)
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
gig [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VW83
Gene Names
gig
Reference Genes
BioGPS Gene:40201 gig
ENSEMBL:FBgn0005198
FlyBase:FBgn0005198
Monarch:40201 gig
NCBI Gene:40201 gig
UCSC:Q9VW83 gig
Reference Transcript
RefSeq:NM_079453.3 gig
Other Identifiers
154762_at
1632822_at
40201
GO:0001934
GO:0002376
GO:0005096
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006914
GO:0007165
GO:0007584
GO:0008285
GO:0008340
GO:0010508
GO:0019900
GO:0019901
GO:0022414
GO:0023052
GO:0030154
GO:0030178
GO:0030308
GO:0030948
GO:0032007
GO:0033596
GO:0034330
GO:0035069
GO:0036211
GO:0042325
GO:0042632
GO:0043226
GO:0043547
GO:0045792
GO:0045886
GO:0046621
GO:0046627
GO:0048477
GO:0048542
GO:0048856
GO:0051056
GO:0051726
GO:0051898
GO:0055088
GO:0071456
GO:0098772
GO:1902350
GO:1904262
GO:1904504
GO:1904515
GO:2000331
Participates
as an input of
Phosphorylation of TSC2 by PKB (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
Formation of TSC1:TSC2 complex (Drosophila melanogaster)
as a component of
TSC1:TSC2 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-gig [cytosol]
phospho-gig [cytosol]
phospho-gig [cytosol]
Inferred From
TSC2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_524177.1
Flybase
FBgn0005198
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