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cPges [cytosol]
Stable Identifier
R-DME-265269
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
PTGES3, Q9VH95
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to heat stress (Drosophila melanogaster)
HSF1 activation (Drosophila melanogaster)
Dissociation of cytosolic HSF1:HSP90 complex (Drosophila melanogaster)
HSF1:HSP90:PTGES3 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Drosophila melanogaster)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Drosophila melanogaster)
AR binds AR agonists (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:AR agonists [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
AR binds AR antagonists (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
Androgens binds AR (in the HSP90 chaperone complex) (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C1 binds NR3C1 agonists (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C2 binds NR3C2 antagonists (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C2:NR3C2 antagonists [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C2 binds fludrocortisone (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C2:fludrocortisone [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
P4 bind PGR (in the HSP90 chaperone complex) (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
PGR binds PGR agonists (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
PGR:PGR agonists [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
PGR binds PGR antagonists (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
PGR:PGR antagonists [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Drosophila melanogaster)
HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Aryl hydrocarbon receptor signalling (Drosophila melanogaster)
AHR:2xHSP90:AIP:PTGES3 binds TCDD (Drosophila melanogaster)
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol] (Drosophila melanogaster)
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Drosophila melanogaster)
AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol] (Drosophila melanogaster)
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Arachidonate metabolism (Drosophila melanogaster)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Drosophila melanogaster)
Prostaglandin E synthase isomerizes PGH2 to PGE2 (Drosophila melanogaster)
PTGES2(88-377), PTGES3 [cytosol] (Drosophila melanogaster)
cPges [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VH95
Gene Names
cPges
Reference Genes
BioGPS Gene:41173 cPges
ENSEMBL:FBgn0037728
FlyBase:FBgn0037728
KEGG:dme:Dmel_CG16817 cPges
Monarch:41173 cPges
NCBI Gene:41173 cPges
UCSC:Q9VH95 cPges
Reference Transcript
RefSeq:NM_001260081.2 cPges
RefSeq:NM_141668.3 cPges
Other Identifiers
154167_at
1628784_at
41173
GO:0005634
GO:0005737
GO:0005783
GO:0005829
GO:0006457
GO:0016853
GO:0031965
GO:0050220
GO:0051087
GO:0051131
GO:0051879
GO:0065003
GO:0070922
Participates
as a member of
PTGES2(88-377), PTGES3 [cytosol] (Drosophila melanogaster)
as a component of
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:AR agonists [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Drosophila melanogaster)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Drosophila melanogaster)
HSF1:HSP90:PTGES3 [cytosol] (Drosophila melanogaster)
as an input of
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Drosophila melanogaster)
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Drosophila melanogaster)
as an output of
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Drosophila melanogaster)
Dissociation of cytosolic HSF1:HSP90 complex (Drosophila melanogaster)
Other forms of this molecule
cPges [nucleoplasm]
Inferred From
PTGES3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001247010.1
,
NP_649925.1
ENSEMBL
FBtr0082082
,
FBpp0300672
,
FBtr0308353
,
FBpp0081560
,
FBgn0037728
IntEnz
5.3.99.3
FlyBase
FBgn0037728
PRO
Q9VH95
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