Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
DNM2 [cytosol]
Stable Identifier
R-DME-2213180
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P27619
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Dynamin [cytosol] (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
trans-Golgi Network Vesicle Budding (Drosophila melanogaster)
Golgi Associated Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Coat Assembly (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
Lysosome Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Drosophila melanogaster)
DNM2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P27619
Reference Genes
BioGPS Gene:45928
CTD Gene:45928
ENSEMBL:FBgn0003392
Flybase:FBgn0003392
KEGG Gene (Drosophila melanogaster):Dmel_CG18102
Monarch:45928
NCBI Gene:45928
UCSC:P27619
Reference Transcript
RefSeq:NM_001169297.2
RefSeq:NM_080114.4
RefSeq:NM_206743.2
RefSeq:NM_206744.3
RefSeq:NM_167470.3
RefSeq:NM_001169295.1
RefSeq:NM_001042813.2
RefSeq:NM_206745.3
RefSeq:NM_001042814.2
RefSeq:NM_167471.5
RefSeq:NM_206742.1
Other Identifiers
154032_at
1625442_a_at
1637637_at
45928
GO:0000166
GO:0000278
GO:0000910
GO:0001661
GO:0001738
GO:0001933
GO:0003779
GO:0003824
GO:0003924
GO:0005525
GO:0005737
GO:0005856
GO:0005874
GO:0005886
GO:0006897
GO:0006898
GO:0006914
GO:0007010
GO:0007268
GO:0007291
GO:0007298
GO:0007349
GO:0007424
GO:0007427
GO:0007435
GO:0007612
GO:0007613
GO:0007614
GO:0007637
GO:0008017
GO:0008092
GO:0008355
GO:0010508
GO:0012501
GO:0016020
GO:0016185
GO:0016192
GO:0016787
GO:0022414
GO:0023052
GO:0030154
GO:0030198
GO:0030536
GO:0030707
GO:0030838
GO:0030866
GO:0031594
GO:0032956
GO:0032970
GO:0034330
GO:0034334
GO:0035152
GO:0035186
GO:0036211
GO:0036465
GO:0040008
GO:0043226
GO:0045202
GO:0046667
GO:0046718
GO:0046843
GO:0048172
GO:0048488
GO:0048489
GO:0048499
GO:0048856
GO:0048870
GO:0050803
GO:0050877
GO:0061024
GO:0061883
GO:0065003
GO:0070864
GO:0072583
GO:0072659
GO:0072686
GO:0090148
GO:0098793
GO:0099525
GO:0150007
GO:0150008
GO:1903475
Participates
as an output of
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
as an input of
trans-Golgi Network Coat Assembly (Drosophila melanogaster)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Drosophila melanogaster)
as a member of
Dynamin [cytosol] (Drosophila melanogaster)
Other forms of this molecule
DNM2 [Golgi membrane]
DNM1 [cytosol]
DNM3 [cytosol]
DNM3 [plasma membrane]
DNM2 [lysosomal membrane]
DNM1 [lysosomal membrane]
DNM2 [plasma membrane]
DNM1 [plasma membrane]
Inferred From
DNM2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001036278.1
,
NP_001036279.1
,
NP_001162766.1
,
NP_001162768.1
,
NP_996468.1
,
NP_996466.1
,
NP_996465.1
,
NP_727911.1
,
NP_727910.1
,
NP_524853.2
,
NP_996467.1
Flybase
FBgn0003392
IntEnz
3.6.5.5
PRO
P27619
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text