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shi [cytosol]
Stable Identifier
R-DME-2213180
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
DNM2, P27619
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
DNM:GDP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
trans-Golgi Network Vesicle Budding (Drosophila melanogaster)
Golgi Associated Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Coat Assembly (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
Lysosome Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Drosophila melanogaster)
shi [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P27619
Gene Names
shi
Reference Genes
BioGPS Gene:45928 shi
CTD Gene:45928 shi
ENSEMBL:FBgn0003392
FlyBase:FBgn0003392
KEGG:dme:Dmel_CG18102 shi
Monarch:45928 shi
NCBI Gene:45928 shi
UCSC:P27619 shi
Reference Transcript
RefSeq:NM_206743.2 shi
RefSeq:NM_001169295.1 shi
RefSeq:NM_167471.5 shi
RefSeq:NM_001169297.2 shi
RefSeq:NM_167470.3 shi
RefSeq:NM_080114.4 shi
RefSeq:NM_206742.1 shi
RefSeq:NM_001042814.2 shi
RefSeq:NM_206745.3 shi
RefSeq:NM_001042813.2 shi
RefSeq:NM_206744.3 shi
Other Identifiers
154032_at
1625442_a_at
1628859_at
1637637_at
45928
GO:0000166
GO:0000278
GO:0001661
GO:0001738
GO:0001933
GO:0003779
GO:0003924
GO:0005525
GO:0005737
GO:0005819
GO:0005856
GO:0005874
GO:0005886
GO:0006897
GO:0006898
GO:0007010
GO:0007268
GO:0007291
GO:0007298
GO:0007349
GO:0007424
GO:0007427
GO:0007435
GO:0007612
GO:0007613
GO:0007614
GO:0007637
GO:0008017
GO:0008092
GO:0008355
GO:0010508
GO:0012501
GO:0016185
GO:0016192
GO:0016787
GO:0030198
GO:0030536
GO:0030707
GO:0030838
GO:0030866
GO:0031594
GO:0031623
GO:0032956
GO:0032970
GO:0034330
GO:0034334
GO:0035152
GO:0035186
GO:0036465
GO:0040008
GO:0043226
GO:0045202
GO:0046667
GO:0046718
GO:0046843
GO:0048172
GO:0048488
GO:0048489
GO:0048499
GO:0048856
GO:0048870
GO:0050803
GO:0050877
GO:0061024
GO:0061883
GO:0070864
GO:0072583
GO:0072659
GO:0072686
GO:0090148
GO:0098793
GO:0099525
GO:0150007
GO:0150008
GO:1903475
Participates
as an output of
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
as an input of
trans-Golgi Network Coat Assembly (Drosophila melanogaster)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Drosophila melanogaster)
as a component of
DNM:GDP [cytosol] (Drosophila melanogaster)
DNM:GTP [cytosol] (Drosophila melanogaster)
Other forms of this molecule
shi [plasma membrane]
shi [plasma membrane]
shi [lysosomal membrane]
shi [lysosomal membrane]
shi [plasma membrane]
shi [cytosol]
shi [cytosol]
shi [Golgi membrane]
Inferred From
Dynamin [cytosol]
(Homo sapiens)
DNM2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_996468.1
,
NP_001036279.1
,
NP_727911.1
,
NP_996467.1
,
NP_996466.1
,
NP_727910.1
,
NP_524853.2
,
NP_996465.1
,
NP_001036278.1
,
NP_001162766.1
,
NP_001162768.1
ENSEMBL
FBtr0301595
,
FBtr0074123
,
FBpp0089277
,
FBtr0301594
,
FBtr0074124
,
FBpp0290810
,
FBpp0089280
,
FBgn0003392
,
FBpp0290809
IntEnz
3.6.5.5
PRO
P27619
FlyBase
FBgn0003392
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