AP-1 transcription factor, JRA:KAY, is phosphorylated by phosphorylated BSK kinase

Stable Identifier
R-DME-209381
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Phosphorylated Basket (BSK) kinase phosphorylates residues Ser82 and Ser92 on JRA along with residues Thr216 and Thr220 on KAY.
Literature References
PubMed ID Title Journal Year
1749429 Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

Karin, M, Binetruy, B, Mercola, DA, Smeal, T, Birrer, M

Nature 1991
8946915 A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

Davis, RJ, Sluss, HK, Han, Z, Ip, YT, Barrett, T

Genes Dev 1996
11865058 CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila

Marinissen, MJ, Hou, SX, Chen, X, Chen, HW, Oh, SW, Gutkind, JS, Melnick, M, Perrimon, N

Mol Cell Biol 2002
1922387 Phosphorylation of c-jun mediated by MAP kinases

Woodgett, JR, Kyriakis, JM, Pulverer, BJ, Nikolakaki, E, Avruch, J

Nature 1991
8946916 The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye

Fritz, A, Hafen, E, Riesgo-Escovar, JR, Jenni, M

Genes Dev 1996
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of Phospho BSK:CKA:JRA:KAY [nucleoplasm]

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