Reactome | Phosphorylated REL-68 transports from the cytosol to the nucleus

Phosphorylated REL-68 transports from the cytosol to the nucleus

Stable Identifier

R-DME-209309

Type

Reaction [transition]

Species

Drosophila melanogaster

Compartment

nuclear envelope

ReviewStatus

5/5

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Phosphorylated REL-68 transports from the cytosol to the nucleus

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The phosphorylated N-terminal cleaved domain of Relish (REL-68) translocates from the cytosol to the nucleus. The corresponding phosphorylated C-terminal cleaved domain (REL-49) remains in the cytoplasm.

Literature References

PubMed ID	Title	Journal	Year
11269501	Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage Ando, I, Engstrom, Y, Kadalayil, L, Hultmark, D, Stoven, S	EMBO Rep	2000
12732719	Caspase-mediated processing of the Drosophila NF-kappaB factor Relish Erturk, D, Hedengren-Olcott, M, Silverman, N, Engstrom, Y, Junell, A, Hultmark, D, Maniatis, T, Stoven, S	Proc Natl Acad Sci U S A	2003