HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex

Stable Identifier
R-DME-209200
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
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HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex
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MAP kinase kinase orthologue, the dual specificity kinase Hemipterous (HEP), is phosphorylated and activated in its activation loop at residues Ser348 and Thr352 by the MAP kinase kinase kinase orthologue, phosphorylated TAK1.
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Catalyst Activity

protein serine/threonine kinase activity of UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol]

Physical Entity
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
Activity
protein serine/threonine kinase activity (GO:0004674)
Inferred From
Murine MKK4 kinase is phosphorylated and activated by Phospho TAK1:Phospho TAB1:Phospho TAB2 kinase complex (Mus musculus)
Authored
Williams, MG  (2007-07-11)
Reviewed
Lemaitre, B  (2008-06-20)
Silverman, N  (2008-06-20)
Created
Williams, MG  (2007-07-12)
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