Reactome | ARM displaces GRO and binds to PAN which activates transcription

ARM displaces GRO and binds to PAN which activates transcription

Stable Identifier

R-DME-209181

Type

Reaction [transition]

Species

Drosophila melanogaster

Compartment

nucleoplasm

ReviewStatus

5/5

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ARM displaces GRO and binds to PAN which activates transcription

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Armadillo (ARM) in its complex binds to Pangolin (PAN) and transcription is now activated.

Literature References

PubMed ID	Title	Journal	Year
15768032	Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation Weis, WI, Daniels, DL	Nat Struct Mol Biol	2005
16169192	Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins Stadeli, R, Basler, K	Mech Dev	2005
15043810	A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes Thompson, BJ	Curr Biol	2004
11955446	Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex Murone, M, Froesch, B, Basler, K, Nellen, D, Kramps, T, Zullig, S, Brunner, E, Chatterjee, S, Peter, O	Cell	2002

Participants

Input

Output

Participates

as an event of

Transcription activation by ARM (Drosophila melanogaster)

Authored

Williams, MG (2006-07-26)

Reviewed

Nusse, R (2008-01-19)

Created

Williams, MG (2006-06-28)

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