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WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane]
Stable Identifier
R-DME-206993
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM (Drosophila melanogaster)
Destabilisation and degradation of AXN in the 'destruction complex' (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
Participants
components
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol]
(Drosophila melanogaster)
DSH [cytosol]
(Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane]
(Drosophila melanogaster)
Participates
as an output of
Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM (Drosophila melanogaster)
as an input of
Destabilisation and degradation of AXN in the 'destruction complex' (Drosophila melanogaster)
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