Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
BMP2 dimer [extracellular region]
Stable Identifier
R-DME-201463
Type
Complex
Species
Drosophila melanogaster
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by BMP (Drosophila melanogaster)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Drosophila melanogaster)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
An anchoring protein, Endofin, recruits R-Smad1/5/8 (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP2 binds to the receptor complex (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:BMPRII:BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
I-Smad competes with R-Smad1/5/8 for type I receptor (Drosophila melanogaster)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
Phospho-R-Smad1/5/8 dissociates from the receptor complex (Drosophila melanogaster)
BMP:p-BMPR:Endofin [early endosome membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
Type II receptor phosphorylates type I receptor (Drosophila melanogaster)
BMP:BMPRII:BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP2 dimer [extracellular region] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
Homologues of BMP2 [extracellular region]
(Drosophila melanogaster)
Participates
as an input of
BMP2 binds to the receptor complex (Drosophila melanogaster)
as a component of
BMP:BMPRII:BMPRI [plasma membrane] (Drosophila melanogaster)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Drosophila melanogaster)
BMP:p-BMPR:Endofin [early endosome membrane] (Drosophila melanogaster)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Drosophila melanogaster)
Inferred From
BMP2 dimer [extracellular region]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text