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About
What is Reactome ?
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Team
Scientific Advisory Board
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FYN [cytosol]
Stable Identifier
R-DME-200917
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P00528
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Drosophila melanogaster)
Nephrin family interactions (Drosophila melanogaster)
Nephrin binds NCK (Drosophila melanogaster)
NEPH1:p-Nephrin:Fyn:NCK [plasma membrane] (Drosophila melanogaster)
p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Nephrin dimer:KIRREL binds FYN (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
NPHS1 dimer:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Nephrin interacts with Podocin (Drosophila melanogaster)
Podocin:p-Nephrin:Fyn:NEPH1 [plasma membrane] (Drosophila melanogaster)
p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Phosphorylation of nephrin by FYN (Drosophila melanogaster)
NPHS1 dimer:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPH-ephrin mediated repulsion of cells (Drosophila melanogaster)
EPHA binds TIAM1 (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
SFKs phosphorylate VAV2,3 (Drosophila melanogaster)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Drosophila melanogaster)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Drosophila melanogaster)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Drosophila melanogaster)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-EPHs bind VAV2,3 (Drosophila melanogaster)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Drosophila melanogaster)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHA-mediated growth cone collapse (Drosophila melanogaster)
NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs:p-Y179-NGEF [plasma membrane] (Drosophila melanogaster)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
EPHB phosphorylates TIAM1 (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHB:NMDAR binds TIAM1 (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Drosophila melanogaster)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Ephrin signaling (Drosophila melanogaster)
EFNB:GRB4 binds GIT1 (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EFNBs bind SFKs (Drosophila melanogaster)
EPHBs:EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
GIT1 binds bPIX (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
PAK binds RAC and bPIX (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
PAKs autophosphorylate (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
PAKs phosphorylate MLC (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
bPIX exchanges GTP for GDP on RAC, activating it (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-EFNB binds GRB4 (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Phosphorylation of DCC by Fyn (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Semaphorin interactions (Drosophila melanogaster)
CRMPs in Sema3A signaling (Drosophila melanogaster)
Phosphorylation of CRMPs by Cdk5 (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's [plasma membrane] (Drosophila melanogaster)
NRP1:PlexinA1-4:FYN:Cdk5:p53:p-CRMP tetramers [plasma membrane] (Drosophila melanogaster)
PlexinA1-4:FYN:Cdk5:p35:p-CRMP tetramers [plasma membrane] (Drosophila melanogaster)
Fyn:pCdk5:p35 [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Fyn:pCdk5 [plasma membrane] (Drosophila melanogaster)
NRP1:PlexinA1-4:FYN:pCdk5:p53 [plasma membrane] (Drosophila melanogaster)
PlexinA1-4:FYN:pCdk5:p35 [plasma membrane] (Drosophila melanogaster)
Fyn:pCdk5:p35 [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Phosphorylation of CRMPs by GSK3beta (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's [plasma membrane] (Drosophila melanogaster)
NRP1:PlexinA1-4:FYN:Cdk5:p53:p-CRMP tetramers [plasma membrane] (Drosophila melanogaster)
PlexinA1-4:FYN:Cdk5:p35:p-CRMP tetramers [plasma membrane] (Drosophila melanogaster)
Fyn:pCdk5:p35 [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Tyrosine phosphorylation of CRMPs by Fes (Drosophila melanogaster)
Sema3A:NP-1:Plexin-A:Fes:CRMP [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (Drosophila melanogaster)
Sema3A binds Nrp-1 bound to PlexinA (Drosophila melanogaster)
NRP1:PlexinA1-4:FARP2:FYN [plasma membrane] (Drosophila melanogaster)
Plexin-A1-4:FYN:FARP2 [plasma membrane] (Drosophila melanogaster)
Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Sema3A:Nrp-1:Plexin A:Fyn [plasma membrane] (Drosophila melanogaster)
NRP1:Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Sema3A PAK dependent Axon repulsion (Drosophila melanogaster)
Activation of PAK by Rac1 (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Drosophila melanogaster)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Drosophila melanogaster)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Drosophila melanogaster)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Drosophila melanogaster)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Drosophila melanogaster)
Sema3A:NRP-1:pPlexin-A:fyn [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Drosophila melanogaster)
Regulation of signaling by CBL (Drosophila melanogaster)
CBL ubiquitinates PI3K (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
FYN-like kinases [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
FYN-like kinases [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Drosophila melanogaster)
FYN-like kinases [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
FYN-like kinases [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
C-type lectin receptors (CLRs) (Drosophila melanogaster)
CD209 (DC-SIGN) signaling (Drosophila melanogaster)
SFKs phosphorylates RAF1 on Y340,Y341 (Drosophila melanogaster)
FYN, LYN [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by SCF-KIT (Drosophila melanogaster)
Dimerization of STATs (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Disassociation and translocation of STATs to the nucleus (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Phosphorylation of JAK2 (Drosophila melanogaster)
JAK2:SFKS:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Phosphorylation of STATs (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Recruitment of STATs (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Regulation of KIT signaling (Drosophila melanogaster)
Phosphorylation of APS (Drosophila melanogaster)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
p-APS dimer:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Recruitment of CBL to KIT (Drosophila melanogaster)
CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane] (Drosophila melanogaster)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Drosophila melanogaster)
p-APS dimer:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Drosophila melanogaster)
p-APS dimer:p-KIT complex [plasma membrane] (Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
FYN autophosphorylates (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Drosophila melanogaster)
FYN [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P00528
Reference Genes
BioGPS Gene:48973
CTD Gene:48973
ENSEMBL:FBgn0262733
Flybase:FBgn0262733
KEGG Gene (Drosophila melanogaster):Dmel_CG7524
Monarch:48973
NCBI Gene:48973
Reference Transcript
RefSeq:NM_080195.4
RefSeq:NM_001202122.1
RefSeq:NM_001014562.3
RefSeq:NM_001014561.2
RefSeq:NM_001259700.2
RefSeq:NM_001014564.3
RefSeq:NM_001014563.3
RefSeq:NM_001259699.2
Other Identifiers
143366_at
1634871_s_at
1641253_at
48973
GO:0000166
GO:0002009
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005515
GO:0005524
GO:0005829
GO:0005886
GO:0006468
GO:0007010
GO:0007155
GO:0007169
GO:0007293
GO:0007300
GO:0007301
GO:0007349
GO:0007411
GO:0007424
GO:0007435
GO:0007616
GO:0008064
GO:0008302
GO:0008335
GO:0009887
GO:0016043
GO:0016301
GO:0016310
GO:0016319
GO:0016740
GO:0018108
GO:0022414
GO:0023052
GO:0030036
GO:0030046
GO:0030154
GO:0030708
GO:0030717
GO:0030723
GO:0031234
GO:0034330
GO:0034332
GO:0035332
GO:0036058
GO:0036211
GO:0045087
GO:0045172
GO:0045742
GO:0045743
GO:0045874
GO:0045886
GO:0048167
GO:0048468
GO:0048477
GO:0048513
GO:0048856
GO:0050877
GO:0065008
GO:0090136
GO:0098542
GO:0120176
GO:0140096
Participates
as a member of
SRC,FYN [cytosol] (Drosophila melanogaster)
FYN-like kinases [cytosol] (Drosophila melanogaster)
FYN, LYN [cytosol] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
as an input of
Nephrin dimer:KIRREL binds FYN (Drosophila melanogaster)
as a component of
NPHS1 dimer:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] (Drosophila melanogaster)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Drosophila melanogaster)
NRP1:Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
Fyn:pCdk5:p35 [plasma membrane] (Drosophila melanogaster)
NRP1:p-Plexin-A1-4:FYN [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
MyrG2-PalmC3-LYN [lysosomal membrane]
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
phospho-p-HCK [cytosol]
FGR [extracellular region]
FGR [secretory granule lumen]
SRC [cytosol]
phospho-p-Y419-SRC [cytosol]
phospho-p-S21,Y420-FYN [cytosol]
MyrG-SRC [plasma membrane]
phospho-p-Y419-SRC-1 [plasma membrane]
phospho-p-Y394-LCK [plasma membrane]
LYN [plasma membrane]
phospho-p-Y397-LYN [cytosol]
phospho-p-Y397-LYN [plasma membrane]
SRC-2 [cytosol]
LCK [cytosol]
phospho-MyrG-p-Y419-SRC [plasma membrane]
phospho-MyrG-p-Y426-YES1 [plasma membrane]
phospho-MyrG-p-Y420-FYN-1 [plasma membrane]
phospho-MyrG,p-Y530-SRC [plasma membrane]
phospho-p-Y420-FYN [cytosol]
LYN [cytosol]
phospho-p-Y419-SRC [cytosol]
SRC-1 [plasma membrane]
FGR [cytosol]
YES1 [cytosol]
HCK [cytosol]
MyrG2-PalmC3-LYN [plasma membrane]
Inferred From
FYN [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001014561.1
,
NP_001014563.1
,
NP_524934.2
,
NP_001014562.1
,
NP_001014564.1
,
NP_001246628.1
,
NP_001189051.1
,
NP_001246629.1
Flybase
FBgn0262733
PRO
P00528
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q03720
1
slo [plasma membrane]
(R-DME-2534368)
0.544
3
UniProt:P11346 Raf
20
Phospho PHL [plasma membrane]
(R-DME-205859)
PHL [cytosol]
(R-DME-205713)
phospho-p-S338,Y340,Y341-RAF1 [cytosol]
(R-DME-5624465)
phospho-p-S338-RAF1 [cytosol]
(R-DME-5624469)
BRAF [cytosol]
(R-DME-167224)
phospho-hyperphosphorylated BRAF [plasma membrane]
(R-DME-5675199)
phospho-hyperphosphorylated RAF1 [plasma membrane]
(R-DME-5675193)
phospho-p-S299,S302,T452,T455,S582 ARAF [cytosol]
(R-DME-5672646)
phospho-p-S446,T599,S602,S729 BRAF [cytosol]
(R-DME-5672676)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-DME-5672664)
phospho-p-S446,S729-BRAF [cytosol]
(R-DME-5672673)
phospho-p-S446,T599,S602,S729 BRAF [plasma membrane]
(R-DME-5672679)
phospho-p-S299,S302,T452,T455,S582 ARAF [plasma membrane]
(R-DME-5672648)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-DME-5672665)
phospho-p-S582 ARAF [cytosol]
(R-DME-5672681)
phospho-p-S621-RAF1 [cytosol]
(R-DME-206028)
RAF1 [cytosol]
(R-DME-167205)
phospho-p-S214,S582 ARAF [cytosol]
(R-DME-5672639)
phospho-p-S259,S621-RAF1 [cytosol]
(R-DME-109786)
phospho-p-S365,S446,S729 BRAF [cytosol]
(R-DME-5672667)
0.544
3
UniProt:Q9VLA2 GCM2
0.488
2
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