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trbl [plasma membrane]
Stable Identifier
R-DME-199447
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
TRIB3, Q9V3Z1
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Costimulation by the CD28 family (Drosophila melanogaster)
CD28 co-stimulation (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V3Z1
Gene Names
trbl
Reference Genes
BioGPS Gene:43999 trbl
CTD Gene:43999 trbl
ENSEMBL:FBgn0028978
Flybase:FBgn0028978
KEGG Gene (Drosophila melanogaster):Dmel_CG5408 trbl
Monarch:43999 trbl
NCBI Gene:43999 trbl
UCSC:Q9V3Z1 trbl
Reference Transcript
RefSeq:NM_079933.4 trbl
Other Identifiers
149123_at
1629044_at
43999
GO:0000278
GO:0003674
GO:0004672
GO:0004860
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0005938
GO:0006464
GO:0006468
GO:0006469
GO:0007049
GO:0007165
GO:0007370
GO:0008150
GO:0009056
GO:0009790
GO:0010888
GO:0016301
GO:0019899
GO:0030234
GO:0031434
GO:0032436
GO:0040007
GO:0042592
GO:0042593
GO:0042803
GO:0043167
GO:0043226
GO:0043405
GO:0045793
GO:0045839
GO:0046627
GO:0046982
GO:0048640
GO:0048646
GO:0048856
GO:0051726
GO:0051898
GO:0140014
GO:2000060
Participant Of
input
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation
hasComponent
AKT:PIP3:THEM4/TRIB3 [plasma membrane]
Other forms of this molecule
trbl [cytosol]
Inferred From
TRIB3 [plasma membrane] (Homo sapiens)
THEM4/TRIB3 [plasma membrane] (Homo sapiens)
Cross References
RefSeq
NP_524672.1
Flybase
FBgn0028978
PRO
Q9V3Z1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VXS3 Q9VXS3
0.621
4
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