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trbl [plasma membrane]
Stable Identifier
R-DME-199447
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
TRIB3, Q9V3Z1
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Regulation of T cell activation by CD28 family (Drosophila melanogaster)
Co-stimulation by CD28 (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
trbl [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V3Z1
Gene Names
trbl
Reference Genes
BioGPS Gene:43999 trbl
CTD Gene:43999 trbl
ENSEMBL:FBgn0028978
FlyBase:FBgn0028978
KEGG:dme:Dmel_CG5408 trbl
Monarch:43999 trbl
NCBI Gene:43999 trbl
UCSC:Q9V3Z1 trbl
Reference Transcript
RefSeq:NM_079933.4 trbl
Other Identifiers
149123_at
1629044_at
43999
GO:0003824
GO:0004672
GO:0004860
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005938
GO:0006468
GO:0007049
GO:0007370
GO:0010888
GO:0016740
GO:0031434
GO:0032436
GO:0042593
GO:0042803
GO:0043226
GO:0043405
GO:0045793
GO:0045839
GO:0046627
GO:0046982
GO:0048640
GO:0051726
GO:0051898
GO:0098772
GO:0140096
GO:2000060
Participates
as an input of
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Drosophila melanogaster)
as a component of
AKT:PIP3:THEM4/TRIB3 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
trbl [cytosol]
Inferred From
THEM4/TRIB3 [plasma membrane]
(Homo sapiens)
TRIB3 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_524672.1
ENSEMBL
FBtr0078235
,
FBpp0077893
PRO
Q9V3Z1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VXS3 Q9VXS3
0.621
4
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