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Phosphorylated ERBB2:EGFR heterodimers [plasma membrane]
Stable Identifier
R-DME-1963587
Type
Set [CandidateSet]
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
Downregulation of ERBB2 signaling (Drosophila melanogaster)
PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
PI3K events in ERBB2 signaling (Drosophila melanogaster)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Drosophila melanogaster)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Drosophila melanogaster)
Participants
members
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane]
(Drosophila melanogaster)
candidates
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane]
(Drosophila melanogaster)
Participates
as a component of
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Drosophila melanogaster)
as an input of
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Drosophila melanogaster)
Inferred From
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane]
(Homo sapiens)
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