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RtGEF [cytosol]
Stable Identifier
R-DME-195017
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
ARHGEF6, A8DZ19
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Drosophila melanogaster)
Cell junction organization (Drosophila melanogaster)
Cell-extracellular matrix interactions (Drosophila melanogaster)
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components (Drosophila melanogaster)
PARVB/Affixin interacts with alpha PIX (Drosophila melanogaster)
ParvB/Affixin:Alpha-Pix [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Death Receptor Signalling (Drosophila melanogaster)
p75 NTR receptor-mediated signalling (Drosophila melanogaster)
Cell death signalling via NRAGE, NRIF and NADE (Drosophila melanogaster)
NRAGE signals death through JNK (Drosophila melanogaster)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Drosophila melanogaster)
GEFs [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
GEFs activate RhoA,B,C (Drosophila melanogaster)
GEFs [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through CDC42 (Drosophila melanogaster)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
PAK1 binds ARHGEF6 (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Drosophila melanogaster)
Active PAK1:ARHGEF6 [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
Rho GTPase cycle (Drosophila melanogaster)
GEFs activate Rho GTPase:GDP (Drosophila melanogaster)
GEFs [cytosol] (Drosophila melanogaster)
RtGEF [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A8DZ19
Gene Names
RtGEF
Reference Genes
BioGPS Gene:35306 RtGEF
ENSEMBL:FBgn0015803
Flybase:FBgn0015803
KEGG Gene (Drosophila melanogaster):Dmel_CG10043 RtGEF
Monarch:35306 RtGEF
NCBI Gene:35306 RtGEF
UCSC:A8DZ19 RtGEF
Reference Transcript
RefSeq:NM_001103714.3 RtGEF
Other Identifiers
1639115_s_at
35306
GO:0003674
GO:0005085
GO:0005089
GO:0005515
GO:0005575
GO:0007165
GO:0008150
GO:0019899
GO:0034330
GO:0035023
GO:0035332
GO:0040007
GO:0043226
GO:0043547
GO:0046620
GO:0050807
GO:0060090
GO:0097482
Participant Of
output
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex
input
PAK1 binds ARHGEF6
PARVB/Affixin interacts with alpha PIX
hasComponent
Active PAK1:ARHGEF6 [cytosol]
ParvB/Affixin:Alpha-Pix [cytosol]
hasMember
GEFs [cytosol]
Other forms of this molecule
RtGEF [cytosol]
Inferred From
ARHGEF6 [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_001097184.2
Flybase
FBgn0015803
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