Reactome | SQSTM1 [cytosol]

SQSTM1 [cytosol]

Stable Identifier

R-DME-193937

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

P14199

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P14199

Reference Genes

BioGPS Gene:35246

CTD Gene:35246

ENSEMBL:FBgn0003231

Flybase:FBgn0003231

KEGG Gene (Drosophila melanogaster):Dmel_CG10360

Monarch:35246

NCBI Gene:35246

UCSC:P14199

Reference Transcript

RefSeq:NM_057352.4
RefSeq:NM_001014491.2

Other Identifiers

152056_at

1627212_at

35246

GO:0000423

GO:0003677

GO:0005080

GO:0005515

GO:0005634

GO:0005737

GO:0005773

GO:0005776

GO:0006914

GO:0007005

GO:0007032

GO:0008270

GO:0016235

GO:0030382

GO:0035973

GO:0043226

GO:0044753

GO:0046872

GO:0061912

GO:0070530

Participates

as an input of

SQSTM1 oligomerizes (Drosophila melanogaster)
SQSTM1 binds ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)
p62 binds ubiquitinated mitochondrial substrates (Drosophila melanogaster)

as a component of

SQSTM1 oligomer [cytosol] (Drosophila melanogaster)
ATM dimer:Ub-p-PEX5:SQSTM1 [peroxisomal membrane] (Drosophila melanogaster)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Drosophila melanogaster)

Other forms of this molecule

K7 ub-SQSTM1 [cytosol]

phospho-p-S349 SQSTM1 [cytosol]

phospho-ub K420 p-S349 SQSTM1 [cytosol]

Inferred From

SQSTM1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001014491.1, NP_476700.1

Flybase

FBgn0003231

PRO

P14199