Reactome | Eps-15 [cytosol]

Eps-15 [cytosol]

Stable Identifier

R-DME-182920

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

EPS15, Q9W111

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - Clathrin-mediated endocytosis (Drosophila melanogaster)
    - AAK1 phosphorylates AP-2 mu subunit at T156 (Drosophila melanogaster)
      - PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - BAR domain proteins recruit dynamin (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
      - CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
      - ARBB recruits GPCRs into clathrin-coated pits (Drosophila melanogaster)
        
        ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        UBQLN2:UIM-containing proteins [cytosol] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - Epsin family proteins bind ubiquitinated cargo (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - UBQLNs bind UIM-containing adaptor proteins (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        UNQLNs:UIM proteins [cytosol] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - Clathrin recruits PIK3C2A (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
    - SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
        
        EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)
        
        Eps-15 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9W111

Gene Names

Eps-15

Reference Genes

BioGPS Gene:37961 Eps-15

ENSEMBL:FBgn0035060

FlyBase:FBgn0035060

Monarch:37961 Eps-15

NCBI Gene:37961 Eps-15

UCSC:Q9W111 Eps-15

Reference Transcript

RefSeq:NM_138121.2 Eps-15

Other Identifiers

141766_at

1633729_a_at

37961

GO:0005509

GO:0005515

GO:0005737

GO:0005886

GO:0006897

GO:0008021

GO:0008582

GO:0016192

GO:0016197

GO:0030132

GO:0031410

GO:0031594

GO:0043226

GO:0045746

GO:0048488

GO:0098834

GO:0098894

Participates

as a component of

as a member of

EPS15,EPN1,EPN2 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Eps-15 [cytosol]

phospho-Eps-15 [cytosol]

Eps-15 [plasma membrane]

Inferred From

EPS15 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

FBpp0072340, FBgn0035060, FBtr0072435

FlyBase

FBgn0035060

GlyGen

Q9W111

Cite Us!