Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
IKBKG [cytosol]
Stable Identifier
R-DME-168108
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9GYV5
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to mechanical stimuli (Drosophila melanogaster)
Response of endothelial cells to shear stress (Drosophila melanogaster)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Drosophila melanogaster)
PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus (Drosophila melanogaster)
p-Y187,Y198-CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
Downstream signaling events of B Cell Receptor (BCR) (Drosophila melanogaster)
Activation of NF-kappaB in B cells (Drosophila melanogaster)
Activated IKK phosphorylates I-kappaB (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Interferon Signaling (Drosophila melanogaster)
Antiviral mechanism by IFN-stimulated genes (Drosophila melanogaster)
PKR-mediated signaling (Drosophila melanogaster)
IKK complex is activated by PKR (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-1 family signaling (Drosophila melanogaster)
Interleukin-1 signaling (Drosophila melanogaster)
NEMO binds polyubiquitinated IRAK1 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Poly-K6-Ub-hp-IRAK1:CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Cytosolic sensors of pathogen-associated DNA (Drosophila melanogaster)
ZBP1(DAI) mediated induction of type I IFNs (Drosophila melanogaster)
RIP-mediated NFkB activation via ZBP1 (Drosophila melanogaster)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Drosophila melanogaster)
TRAF6 mediated NF-kB activation (Drosophila melanogaster)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor 3 (TLR3) Cascade (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88-independent TLR4 cascade (Drosophila melanogaster)
TRIF (TICAM1)-mediated TLR4 signaling (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Regulation of NF-kappa B signaling (Drosophila melanogaster)
N4BP1 binds IKBKG (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
USP18 binds IKBKG within IKK complex (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Deubiquitination (Drosophila melanogaster)
Ub-specific processing proteases (Drosophila melanogaster)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Drosophila melanogaster)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
TNF signaling (Drosophila melanogaster)
Regulation of TNFR1 signaling (Drosophila melanogaster)
CHUK, IKBKB phosphorylate CYLD at S418 (Drosophila melanogaster)
IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
GNB2L1 binds IKKA:IKKB:NEMO (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
IKKA:IKKB:NEMO:GNB2L1 [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9GYV5 key
Gene Names
key, IKKGAMMA, CG16910
Chain
chain:1-387
Reference Genes
BioGPS Gene:37967 key
KEGG Gene (Drosophila melanogaster):Dmel_CG16910 key
Monarch:37967 key
NCBI Gene:37967 key
UCSC:Q9GYV5 key
Reference Transcript
RefSeq:NM_079132.4 key
Other Identifiers
153921_at
1623762_at
37967
GO:0002230
GO:0002376
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006955
GO:0006963
GO:0023052
GO:0030163
GO:0043122
GO:0043226
GO:0045087
GO:0045089
GO:0045944
GO:0046872
GO:0050829
GO:0051607
GO:0061057
GO:0070530
GO:0098542
GO:2000647
Participates
as a member of
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Drosophila melanogaster)
as a component of
p-Y187,Y198-CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
IKBKG:N4BP1 [cytosol] (Drosophila melanogaster)
IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] (Drosophila melanogaster)
CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
as an input of
N4BP1 binds IKBKG (Drosophila melanogaster)
CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)
Other forms of this molecule
KEY [cytosol]
OPTN [recycling endosome membrane]
IKBKG [nucleoplasm]
phospho-p-S177-OPTN [nucleoplasm]
phospho-p-S177-OPTN [cytosol]
OPTN [Golgi membrane]
K63polyUb-IKBKG [cytosol]
OPTN [cytosol]
phospho-p-S177,S473,S513-OPTN [cytosol]
Inferred From
IKBKG [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_523856.2
Flybase
FBgn0041205
PRO
Q9GYV5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VEZ5 IKKbeta
8
IRD5 [cytosol]
(R-DME-206001)
Phospho IRD5 [cytosol]
(R-DME-206139)
phospho-p-Y187,Y198-CHUK [cytosol]
(R-DME-9861501)
phospho-p-T23-CHUK [cytosol]
(R-DME-198615)
phospho-p-S176,S180-CHUK [cytosol]
(R-DME-177667)
phospho-p-S177,S181-IKBKB [cytosol]
(R-DME-202506)
CHUK [cytosol]
(R-DME-168104)
IKBKB [cytosol]
(R-DME-168114)
0.632
4
UniProt:P34082
2
Fas2 [extracellular region]
(R-DME-8941043)
Fas2 [plasma membrane]
(R-DME-8940745)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text