Reactome | ND-39 [mitochondrial matrix]

ND-39 [mitochondrial matrix]

Stable Identifier

R-DME-163942

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial matrix

Synonyms

NDUFA9, Q9VPE2

Locations in the PathwayBrowser

Expand all

Metabolism (Drosophila melanogaster)

- Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Drosophila melanogaster)
    - Respiratory electron transport (Drosophila melanogaster)
      - Complex I biogenesis (Drosophila melanogaster)
        
        IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Drosophila melanogaster)
        
        550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        815kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUF subunits bind to form the IP subcomplex (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Drosophila melanogaster)
        
        980kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        815kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
        
        Complex I [mitochondrial inner membrane] (Drosophila melanogaster)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Drosophila melanogaster)
        
        Complex I [mitochondrial inner membrane] (Drosophila melanogaster)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)
        
        ND-39 [mitochondrial matrix] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VPE2

Gene Names

ND-39

Reference Genes

BioGPS Gene:40272 ND-39

ENSEMBL:FBgn0037001

Flybase:FBgn0037001

KEGG Gene (Drosophila melanogaster):Dmel_CG6020 ND-39

Monarch:40272 ND-39

NCBI Gene:40272 ND-39

UCSC:Q9VPE2 ND-39

Reference Transcript

Other Identifiers

153309_at

1633965_at

40272

GO:0003824

GO:0005739

GO:0005747

GO:0006091

GO:0006120

GO:0007005

GO:0016491

GO:0032981

GO:0043226

GO:0044281

GO:0044877

GO:0065003

GO:1901006

Participates

as a component of

NDUFA9:FAD [mitochondrial matrix] (Drosophila melanogaster)

Inferred From

NDUFA9 [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_001262116.1, NP_649234.1

Flybase

FBgn0037001

PDB

8B9Z, 8ESZ, 8BA0, 8ESW

Cite Us!