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Go!
TOP2A [nucleoplasm]
Stable Identifier
R-DME-1362276
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
P15348
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
SUMOylation (Drosophila melanogaster)
SUMO E3 ligases SUMOylate target proteins (Drosophila melanogaster)
SUMOylation of DNA replication proteins (Drosophila melanogaster)
PIAS4 SUMOylates TOP2A with SUMO2,3 (Drosophila melanogaster)
TOP2A [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P15348
Reference Genes
BioGPS Gene:35225
CTD Gene:35225
ENSEMBL:FBgn0284220
Flybase:FBgn0284220
KEGG Gene (Drosophila melanogaster):Dmel_CG10223
Monarch:35225
NCBI Gene:35225
Reference Transcript
RefSeq:NM_001273651.1
RefSeq:NM_057412.5
Other Identifiers
143380_at
1631837_at
35225
GO:0000070
GO:0000166
GO:0000182
GO:0000278
GO:0000400
GO:0000712
GO:0000793
GO:0000819
GO:0003677
GO:0003682
GO:0003696
GO:0003723
GO:0003729
GO:0003824
GO:0003916
GO:0003918
GO:0005515
GO:0005524
GO:0005634
GO:0005694
GO:0005737
GO:0006259
GO:0006265
GO:0006310
GO:0006325
GO:0007059
GO:0007060
GO:0007076
GO:0016787
GO:0016853
GO:0016887
GO:0022414
GO:0030261
GO:0031507
GO:0043226
GO:0046872
GO:0051310
GO:0051321
GO:0140013
GO:0140014
GO:0140097
GO:0140657
Participates
as an input of
PIAS4 SUMOylates TOP2A with SUMO2,3 (Drosophila melanogaster)
Other forms of this molecule
TOP2B [nucleoplasm]
polySUMO2,3-TOP2A [nucleoplasm]
Inferred From
TOP2A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_476760.1
,
NP_001260580.1
Flybase
FBgn0284220
ZINC - Substances
TOP2_DROME
ZINC target
P15348
PRO
P15348
ZINC - Predictions - Purchasable
TOP2_DROME
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:M9PHX2 M9PHX2
0.462
2
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