Reactome | Tim17b2 [mitochondrial inner membrane]

Tim17b2 [mitochondrial inner membrane]

Stable Identifier

R-DME-1252118-3

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial inner membrane

Synonyms

TIMM17A, Q9VJP1

Locations in the PathwayBrowser

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Protein localization (Drosophila melanogaster)

- Mitochondrial protein import (Drosophila melanogaster)
  - TIMM9:TIMM10 transfers proteins to TIMM22 (Drosophila melanogaster)
    - TIMM9:TIMM10:Protein [mitochondrial inner membrane] (Drosophila melanogaster)
      - Proteins Chaperoned by TIMM9:TIMM10 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of TIMM17A [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Tim17b2 [mitochondrial inner membrane] (Drosophila melanogaster)
    - TIMM9:TIMM10:TIMM10B:TIM22:Protein [mitochondrial inner membrane] (Drosophila melanogaster)
      - Proteins Chaperoned by TIMM9:TIMM10 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of TIMM17A [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Tim17b2 [mitochondrial inner membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VJP1

Gene Names

Tim17b2

Reference Genes

BioGPS Gene:44381 Tim17b2

CTD Gene:44381 Tim17b2

ENSEMBL:FBgn0020371

Flybase:FBgn0020371

KEGG Gene (Drosophila melanogaster):Dmel_CG15257 Tim17b2

Monarch:44381 Tim17b2

NCBI Gene:44381 Tim17b2

UCSC:Q9VJP1 Tim17b2

Reference Transcript

Other Identifiers

1635155_a_at

1638375_at

44381

GO:0005215

GO:0005739

GO:0005743

GO:0005744

GO:0006886

GO:0007005

GO:0008320

GO:0010954

GO:0016020

GO:0030150

GO:0043226

GO:0051604

GO:0055085

Participates

as a member of

Homologues of TIMM17A [mitochondrial inner membrane] (Drosophila melanogaster)

Inferred From

TIMM17A [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001285956.1, NP_524746.2

Flybase

FBgn0020371

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9VVX6	3	Bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-DME-5688142) Bet1 [transport vesicle] (R-DME-6808719) Bet1 [Golgi membrane] (R-DME-6807743)	0.488	2
UniProt:Q9VMW8	1	MPDU1 [endoplasmic reticulum membrane] (R-DME-4628428)	0.488	2
UniProt:Q9VL16	4	phospho-Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8948140) phospho-Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8934915) Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8934922) phospho-Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8934910)	0.488	2
UniProt:Q9VCR9	1	Dmel\CG17121 [cytosol] (R-DME-5693370)	0.488	2
UniProt:Q9VHP1	1	Sys1 [trans-Golgi network membrane] (R-DME-6813921)	0.488	2
UniProt:Q9W0N6	2	Vti1a [trans-Golgi network membrane] (R-DME-6813927) Vti1a [Golgi membrane] (R-DME-6811035)	0.488	2
UniProt:Q9VGJ9	7	Q9VGJ9 [nucleoplasm] (R-DME-9708567) Q9VGJ9 [mitochondrial outer membrane] (R-DME-9708524) HMOX2 [plasma membrane] (R-DME-6799676) HMOX2 [specific granule membrane] (R-DME-6799628) HMOX1 [endoplasmic reticulum membrane] (R-DME-189395) HMOX2 [endoplasmic reticulum membrane] (R-DME-189391) Q9VGJ9 [cytosol] (R-DME-9609901)	0.488	2
UniProt:Q7JYX5	5	Vamp7 [clathrin-coated endocytic vesicle membrane] (R-DME-8869135) Vamp7 [cytoplasmic vesicle membrane] (R-DME-376336) Vamp7 [Golgi membrane] (R-DME-266197) Vamp7 [plasma membrane] (R-DME-376361) Vamp7 [lysosomal membrane] (R-DME-376342)	0.488	2
UniProt:Q8T8T9	1	Dmel\CG31717 [plasma membrane] (R-DME-8952144)	0.488	2
UniProt:Q9VCF6	1	Dmel\CG12268 [peroxisomal membrane] (R-DME-390412-8)	0.488	2
UniProt:Q9VTZ5	12	cleaved GPI-MELTF [extracellular region] (R-DME-8941034-2) GPI-MELTF [plasma membrane] (R-DME-8940716-2) TF [secretory granule lumen] (R-DME-350704) LTF [tertiary granule lumen] (R-DME-6800962-2) LTF [specific granule lumen] (R-DME-6799629-2) LTF [extracellular region] (R-DME-977171-2) LTF [phagocytic vesicle lumen] (R-DME-1222567-2) phospho-p-TF [endoplasmic reticulum lumen] (R-DME-8957001) phospho-p-MELTF [endoplasmic reticulum lumen] (R-DME-8957070-2) TF [endoplasmic reticulum lumen] (R-DME-8956763) MELTF [endoplasmic reticulum lumen] (R-DME-8956701-2) apoTF [extracellular region] (R-DME-350754)	0.488	2

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