Reactome | Dif [nucleoplasm]

Dif [nucleoplasm]

Stable Identifier

R-DME-1168585-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

REL, P98149

Locations in the PathwayBrowser

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Immune System (Drosophila melanogaster)

- Adaptive Immune System (Drosophila melanogaster)
  - Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
    - Downstream signaling events of B Cell Receptor (BCR) (Drosophila melanogaster)
      - Activation of NF-kappaB in B cells (Drosophila melanogaster)
        
        NF-kappaB translocates from the cytosol to the nucleus (Drosophila melanogaster)
        
        NF-kappaB p50,p65,c-Rel dimer [nucleoplasm] (Drosophila melanogaster)
        
        NF-kappaB p50:c-Rel [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of REL [nucleoplasm] (Drosophila melanogaster)
        
        Dif [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P98149 Dif

Gene Names

Dif, CG6794

Chain

chain:1-667

Reference Genes

BioGPS Gene:35045 Dif

CTD Gene:35045 Dif

KEGG Gene (Drosophila melanogaster):Dmel_CG6794 Dif

Monarch:35045 Dif

NCBI Gene:35045 Dif

Reference Transcript

Other Identifiers

143643_at

1633246_s_at

35045

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0002225

GO:0002376

GO:0002804

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0006357

GO:0006955

GO:0007249

GO:0007399

GO:0008063

GO:0009605

GO:0010604

GO:0010628

GO:0023052

GO:0030154

GO:0034097

GO:0035070

GO:0035206

GO:0038061

GO:0043226

GO:0045087

GO:0045944

GO:0048468

GO:0048731

GO:0048856

GO:0048935

GO:0050830

GO:0050832

GO:0051173

GO:0098542

GO:0140110

Participates

as a member of

Homologues of REL [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

DIF [cytosol]

Phospho DIF [cytosol]

Phospho DIF [nucleoplasm]

Dif [nucleoplasm]

phospho-Dif [nucleoplasm]

Dif [nucleoplasm]

Dif [cytosol]

Dif [nucleoplasm]

Inferred From

REL [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001162999.1, NP_724050.1, NP_523589.2

Flybase

FBgn0011274

PRO

P98149

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q94527 Rel	16	REL [cytosol] (R-DME-206135) Phospho REL-49 [cytosol] (R-DME-205709) Phospho REL [cytosol] (R-DME-205914) Phospho REL-68 [cytosol] (R-DME-354270) Phospho REL-68 [nucleoplasm] (R-DME-354287) Rel [specific granule lumen] (R-DME-6799557) Rel [extracellular region] (R-DME-6806304) Rel [secretory granule lumen] (R-DME-6801004) Rel [cytosol] (R-DME-2677931) phospho-Rel [cytosol] (R-DME-5607636) phospho-Rel [cytosol] (R-DME-5607629) Rel [cytosol] (R-DME-168168) Rel [cytosol] (R-DME-168144) Rel [nucleoplasm] (R-DME-177674) Rel [nucleoplasm] (R-DME-177655) Rel [cytosol] (R-DME-451607)	0.625	4
UniProt:P84040	14	His4:CG33889 [nucleoplasm] (R-DME-4570531) His4:CG33889 [nucleoplasm] (R-DME-212078) His4:CG33889 [nucleoplasm] (R-DME-4568744) His4:CG33889 [nucleoplasm] (R-DME-5229015) His4:CG33889 [nucleoplasm] (R-DME-4754243) His4:CG33889 [nucleoplasm] (R-DME-4754240) His4:CG33889 [nucleoplasm] (R-DME-5651656) His4:CG33889 [nucleoplasm] (R-DME-427469) His4:CG33889 [nucleoplasm] (R-DME-4568748) His4:CG33889 [nucleoplasm] (R-DME-4568758) His4:CG33889 [nucleoplasm] (R-DME-5423110) His4:CG33889 [nucleoplasm] (R-DME-3451124) His4:CG33889 [nucleoplasm] (R-DME-5651652) His4:CG33889 [nucleoplasm] (R-DME-181902)	0.488	2
UniProt:Q9VD00	1	Dmel\CG5377 [mitochondrial outer membrane] (R-DME-6784968)	0.488	2
UniProt:P51023	4	pnt [nucleoplasm] (R-DME-1629811) pnt [nucleoplasm] (R-DME-1629809) phospho-pnt [nucleoplasm] (R-DME-3132720) phospho-pnt [nucleoplasm] (R-DME-3132735)	0.488	2
UniProt:Q9VMI3	1	ND-51 [mitochondrial inner membrane] (R-DME-163926)	0.488	2

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