Reactome | phospho-Charon [cytosol]

phospho-Charon [cytosol]

Stable Identifier

R-DME-1168563

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

p-S157,S161-Ub-NFKBIE, Q9VPY3

Locations in the PathwayBrowser

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Immune System (Drosophila melanogaster)

- Adaptive Immune System (Drosophila melanogaster)
  - Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
    - Downstream signaling events of B Cell Receptor (BCR) (Drosophila melanogaster)
      - Activation of NF-kappaB in B cells (Drosophila melanogaster)
        
        Ubiquitinated IkB is degraded (Drosophila melanogaster)
        
        NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Drosophila melanogaster)
        
        NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Drosophila melanogaster)
        
        ub-p-IKB alpha,beta,epsilon [cytosol] (Drosophila melanogaster)
        
        phospho-Charon [cytosol] (Drosophila melanogaster)
        
        NF-kappaB p50:p65:ub-p-IKB [cytosol] (Drosophila melanogaster)
        
        ub-p-IKB alpha,beta,epsilon [cytosol] (Drosophila melanogaster)
        
        phospho-Charon [cytosol] (Drosophila melanogaster)
        
        NF-kappaB p65:p65:ub-p-IkB [cytosol] (Drosophila melanogaster)
        
        phospho-Charon [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VPY3

Gene Names

Charon

Reference Genes

BioGPS Gene:33303 Charon

ENSEMBL:FBgn0031317

Flybase:FBgn0031317

KEGG Gene (Drosophila melanogaster):Dmel_CG5118 Charon

Monarch:33303 Charon

NCBI Gene:33303 Charon

UCSC:Q9VPY3 Charon

Reference Transcript

RefSeq:NM_134737.4 Charon

Other Identifiers

153530_at

1629517_at

33303

GO:0001216

GO:0001217

GO:0002376

GO:0003682

GO:0005515

GO:0005634

GO:0006351

GO:0006355

GO:0023052

GO:0032088

GO:0042742

GO:0043226

GO:0045088

GO:0045892

GO:0045893

GO:0048471

GO:0050832

GO:0051059

GO:0051092

GO:0061059

GO:0061060

GO:0098542

GO:0140110

GO:1900424

Participates

as a member of

ub-p-IKB alpha,beta,epsilon [cytosol] (Drosophila melanogaster)

as a component of

NF-kappaB p65:p65:ub-p-IkB [cytosol] (Drosophila melanogaster)

Other forms of this molecule

phospho-Charon [cytosol]

Charon [cytosol]

Inferred From

p-S157,S161-Ub-NFKBIE [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 157 (in Homo sapiens)

Coordinate

157

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 161 (in Homo sapiens)

Coordinate

161

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position

Modification

K48polyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_608581.2

Flybase

FBgn0031317

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