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CycD [nucleoplasm]
Stable Identifier
R-DME-113832
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
CCND1, Q7KUZ5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1 Phase (Drosophila melanogaster)
Cyclin D associated events in G1 (Drosophila melanogaster)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Drosophila melanogaster)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
CDK4/6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CDK4:CCND [nucleoplasm] (Drosophila melanogaster)
CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
Cyclin D1:Cdk6 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Drug-mediated inhibition of CDK4/CDK6 activity (Drosophila melanogaster)
CDK4 inhibitors bind CDK4 (Drosophila melanogaster)
p-T172-CDK4:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1:CDK4 inhibitors (CCND1) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CDK6 inhibitors bind CDK6 (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Drosophila melanogaster)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
CDK4/6:CCND [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CDK4:CCND [nucleoplasm] (Drosophila melanogaster)
CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
Cyclin D1:Cdk6 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Chromatin organization (Drosophila melanogaster)
Chromatin modifying enzymes (Drosophila melanogaster)
RMTs methylate histone arginines (Drosophila melanogaster)
CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Drosophila melanogaster)
CCND1:CDK4:PRMT5:WDR77 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CCND1:CDK4:PRMT5:pT5-WDR77 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Drosophila melanogaster)
CCND1:CDK4:PRMT5:pT5-WDR77:COPRS [nucleoplasm] (Drosophila melanogaster)
CCND1:CDK4:PRMT5:pT5-WDR77 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Drosophila melanogaster)
CCND1:CDK4:PRMT5:pT5-WDR77:COPRS [nucleoplasm] (Drosophila melanogaster)
CCND1:CDK4:PRMT5:pT5-WDR77 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional regulation by RUNX2 (Drosophila melanogaster)
CDK4 phosphorylates RUNX2 (Drosophila melanogaster)
CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Transcriptional regulation by RUNX3 (Drosophila melanogaster)
RUNX3 regulates p14-ARF (Drosophila melanogaster)
CCND1 binds RUNX3 and displaces EP300 (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
CCND1 recruits HDAC4 to RUNX3 (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1:HDAC4 [nucleoplasm] (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
HDAC4 deacetylates RUNX3 (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1:HDAC4 [nucleoplasm] (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
RUNX3:CBFB:CCND1:HDAC4 [nucleoplasm] (Drosophila melanogaster)
CycD [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7KUZ5
Gene Names
CycD
Reference Genes
BioGPS Gene:32551 CycD
ENSEMBL:FBgn0010315
FlyBase:FBgn0010315
KEGG Gene (Drosophila melanogaster):Dmel_CG9096 CycD
Monarch:32551 CycD
NCBI Gene:32551 CycD
Reference Transcript
RefSeq:NM_167473.2 CycD
RefSeq:NM_078631.4 CycD
RefSeq:NM_167472.3 CycD
Other Identifiers
154137_at
1627295_s_at
32551
GO:0000079
GO:0000278
GO:0000307
GO:0003824
GO:0005515
GO:0005634
GO:0005737
GO:0007005
GO:0007049
GO:0010821
GO:0016538
GO:0016740
GO:0023052
GO:0030307
GO:0036211
GO:0043226
GO:0043229
GO:0044772
GO:0046427
GO:0051301
GO:0098772
GO:1900087
GO:1904263
Participates
as a component of
CCND1:CDK4:PRMT5:WDR77 [nucleoplasm] (Drosophila melanogaster)
CCND1:CDK4:PRMT5:pT5-WDR77 [nucleoplasm] (Drosophila melanogaster)
RUNX3:CBFB:CCND1:HDAC4 [nucleoplasm] (Drosophila melanogaster)
Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm] (Drosophila melanogaster)
CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
Cyclin D1:Cdk6 [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
CDK4/6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4:CCND1 [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
as an input of
CCND1 binds RUNX3 and displaces EP300 (Drosophila melanogaster)
Other forms of this molecule
phospho-CycD [cytosol]
phospho-CycD [nucleoplasm]
CycD [cytosol]
CycD [cytosol]
CycD [cytosol]
CycD [nucleoplasm]
CycD [nucleoplasm]
Inferred From
Cyclin D [nucleoplasm]
(Homo sapiens)
CCND1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_523355.2
,
NP_727912.2
,
NP_727913.2
Flybase
FBgn0010315
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