Insulin signaling pathway

Stable Identifier
R-DME-110478
Type
Pathway
Species
Drosophila melanogaster
ReviewStatus
5/5
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In Drosophila there is a single insulin/IGF receptor homologue (DInr), seven insulin-like peptides (DILPs), and a single IRS homologue (Chico), in contrast to the insulin receptor, insulin and IRS entities, respectively, in mammals. DInr and the DILPs interact to regulate growth, haemolymph carbohydrate levels, reproduction and ageing.
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