Activated DINR binds Chico

Stable Identifier
R-DME-110442
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Activated DINR binds Chico
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The Drosophila homologue to mammalian IRS1-4 (Insulin Receptor Substrate), Chico, binds to the beta subunit of DINR. Chico is an adaptor protein that interacts with the activated drosophila insulin-like receptor (DINR), allowing signaling molecules to attach and signal to downstream effectors.
Literature References
PubMed ID Title Journal Year
10455177 The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival.

Garofalo, RS, Marin-Hincapie, M

J Biol Chem 1999
10801879 Characterization of Drosophila insulin receptor substrate.

Taylor, SI, Haft, CR, Xu, P, Poltilove, RM, Jacobs, AR

J Biol Chem 2000
Participants
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Output
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as an event of
Authored
Jassal, B  (2004-02-11)
Created
Jassal, B  (2004-02-11)
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