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GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol]
Stable Identifier
R-DME-109800
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by Insulin receptor (Drosophila melanogaster)
Insulin receptor signalling cascade (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
SOS-mediated signalling (Drosophila melanogaster)
GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Drosophila melanogaster)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Drosophila melanogaster)
Signal attenuation (Drosophila melanogaster)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Drosophila melanogaster)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Drosophila melanogaster)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Drosophila melanogaster)
IGF1R signaling cascade (Drosophila melanogaster)
IRS-related events triggered by IGF1R (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
SOS-mediated signalling (Drosophila melanogaster)
GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Drosophila melanogaster)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GRB2-1:SOS1 [cytosol]
(Drosophila melanogaster)
phospho-chico [cytosol]
(Drosophila melanogaster)
Participates
as an output of
GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Drosophila melanogaster)
as an input of
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Drosophila melanogaster)
as a member of
RAS GEFs [plasma membrane] (Drosophila melanogaster)
Inferred From
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol]
(Homo sapiens)
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