Reactome | mei-P26 [nucleoplasm]

mei-P26 [nucleoplasm]

Stable Identifier

R-DME-1031706

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

PML, A0A4D6K5H4

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A0A4D6K5H4

Gene Names

mei-P26

Reference Genes

ENSEMBL:FBgn0026206

FlyBase:FBgn0026206

Other Identifiers

152315_at

1634020_at

45775

GO:0000785

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006351

GO:0006355

GO:0007276

GO:0007281

GO:0008270

GO:0016567

GO:0016740

GO:0022414

GO:0030154

GO:0036211

GO:0043226

GO:0045893

GO:0046872

GO:0048856

GO:0051321

GO:0060255

GO:0061630

GO:0140096

Participates

as an input of

SUMOylation of PML with SUMO3 (Drosophila melanogaster)
RANBP2 SUMOylates PML with SUMO2 (Drosophila melanogaster)
PML binds RUNX1 (Drosophila melanogaster)
KAT6A and PML bind TP53 (Drosophila melanogaster)

as a component of

RUNX1:PML [nucleoplasm] (Drosophila melanogaster)
KAT6A:ING5:MEAF6:BRPF1,(2,3):PML:Ac-K120,p-S15,S20-TP53 Tetramer [nucleoplasm] (Drosophila melanogaster)
KAT6A:ING5:MEAF6:BRPF1,(2,3):PML:Ac-K120,K382,p-S15,S20-TP53 Tetramer [nucleoplasm] (Drosophila melanogaster)
KAT6A:ING5:MEAF6:BRPF1,(2,3):PML:p-S15,S20-TP53 [nucleoplasm] (Drosophila melanogaster)

This entity regulates

Negatively

USP7 deubiquitinates monoubiquitinated PTEN (Drosophila melanogaster)

Other forms of this molecule

mei-P26 [nucleoplasm]

mei-P26 [cytosol]

Inferred From

PML [nucleoplasm] (Homo sapiens)

Cross References

Flybase

FBgn0026206