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CDC42:GTP, RAC1:GTP [plasma membrane]
Stable Identifier
R-DDI-389778
Type
Set [DefinedSet]
Species
Dictyostelium discoideum
Compartment
plasma membrane
Synonyms
Active RAC1/CDC42
Locations in the PathwayBrowser
Expand all
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Costimulation by the CD28 family (Dictyostelium discoideum)
CD28 co-stimulation (Dictyostelium discoideum)
CD28 dependent Vav1 pathway (Dictyostelium discoideum)
Activation of PAKs by RAC1 and CDC42 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
Innate Immune System (Dictyostelium discoideum)
Fcgamma receptor (FCGR) dependent phagocytosis (Dictyostelium discoideum)
Regulation of actin dynamics for phagocytic cup formation (Dictyostelium discoideum)
Autophosphorylation of PAK1 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK1 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
MAPK family signaling cascades (Dictyostelium discoideum)
MAPK6/MAPK4 signaling (Dictyostelium discoideum)
Activation of PAKs by RAC1 and CDC42 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
Signaling by Rho GTPases (Dictyostelium discoideum)
RHO GTPase Effectors (Dictyostelium discoideum)
RHO GTPases activate IQGAPs (Dictyostelium discoideum)
GTP-bound RAC1 and CDC42 bind IQGAPs (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
IQGAPs bind CALM1 (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RHO GTPases activate PAKs (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK1 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK2 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK3 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
Participants
members
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
Participant Of
hasComponent
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane]
RAC1,CDC42:GTP:IQGAP1 [plasma membrane]
RAC1,CDC42:GTP:IQGAPs [plasma membrane]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane]
input
Activation of PAKs by RAC1 and CDC42
GTP-bound RAC1 and CDC42 bind IQGAPs
RAC1 and CDC42 activate PAK1
RAC1 and CDC42 activate PAK2
RAC1 and CDC42 activate PAK3
output
Autophosphorylation of PAK1
Autophosphorylation of PAK1,2,3
Inferred From
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
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