Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
mTORC1 [cytosol]
Stable Identifier
R-DDI-377400
Type
Complex
Species
Dictyostelium discoideum
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Dictyostelium discoideum)
Macroautophagy (Dictyostelium discoideum)
Active MTORC1 binds the ULK1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Rheb in the MTORC1 complex hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to starvation (Dictyostelium discoideum)
Amino acids regulate mTORC1 (Dictyostelium discoideum)
RRAGA,B hydrolyzes GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1 binds RHEB:GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
Intracellular signaling by second messengers (Dictyostelium discoideum)
PIP3 activates AKT signaling (Dictyostelium discoideum)
PTEN Regulation (Dictyostelium discoideum)
Regulation of PTEN gene transcription (Dictyostelium discoideum)
MAF1 translocates to the nucleus (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1 phosphorylates MAF1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
MTOR signalling (Dictyostelium discoideum)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Energy dependent regulation of mTOR by LKB1-AMPK (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Formation of active mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1-mediated signalling (Dictyostelium discoideum)
Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
lst8 [cytosol]
(Dictyostelium discoideum)
raptor [cytosol]
(Dictyostelium discoideum)
tor [cytosol]
(Dictyostelium discoideum)
Participates
as an input of
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Dictyostelium discoideum)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Dictyostelium discoideum)
as a component of
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
Inferred From
mTORC1 [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text