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O-glycosyl 3a [cytosol]
Stable Identifier
R-COV-9686279
Type
Protein [EntityWithAccessionedSequence]
Species
Human SARS coronavirus
Compartment
cytosol
Synonyms
Protein 3a
GO Cellular Component
host cell cytosol
(0044164)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Defective RIPK1-mediated regulated necrosis (Homo sapiens)
Microbial modulation of RIPK1-mediated regulated necrosis (Homo sapiens)
SARS-CoV-1 3a binds RIPK1:RIPK3 oligomer (Homo sapiens)
SARS-CoV-1 3a:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1 3a binds the lysosomal membrane (Homo sapiens)
3a tetramer:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a tetramer [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1 3a oligomerizes (Homo sapiens)
3a tetramer:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a tetramer [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1 3a:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome (Homo sapiens)
3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane] (Homo sapiens)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1-mediated effects on programmed cell death (Homo sapiens)
SARS-CoV-1 3a binds RIPK1:RIPK3 oligomer (Homo sapiens)
SARS-CoV-1 3a:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1 3a binds the lysosomal membrane (Homo sapiens)
3a tetramer:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a tetramer [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1 3a oligomerizes (Homo sapiens)
3a tetramer:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a tetramer [cytosol] (Human SARS coronavirus)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
SARS-CoV-1 3a:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a [cytosol] (Human SARS coronavirus)
External Reference Information
External Reference
UniProt:P59632 3a
Gene Names
3a
Chain
chain:1-274
Participates
as a component of
3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane] (Homo sapiens)
SARS-CoV-1 3a:(RIPK1:RIPK3) oligomer [cytosol] (Homo sapiens)
O-glycosyl 3a tetramer [cytosol] (Human SARS coronavirus)
as an input of
SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome (Homo sapiens)
SARS-CoV-1 3a binds RIPK1:RIPK3 oligomer (Homo sapiens)
Other forms of this molecule
O-glycosyl 3a [lysosomal membrane]
O-glycosyl 3a [extracellular region]
O-glycosyl 3a [plasma membrane]
3a [endoplasmic reticulum lumen]
3a [endoplasmic reticulum-Golgi intermediate compartment]
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
O-glycosyl 3a [endocytic vesicle membrane]
O-glycosyl 3a [virion membrane]
Modified Residues
Name
O-glycosyl-L-threonine at unknown position
PsiMod Name
O-glycosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine.
Disease
Name
Identifier
Synonyms
severe acute respiratory syndrome
DOID:2945
SARS-CoV infection, SARS
Cross References
PDB
8EQS
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
IntAct:EBI-25589618 SSRNA
0.625
6
UniProt:P59596 M
10
M [plasma membrane]
(R-COV-9731038)
M [Golgi membrane]
(R-COV-9683651)
N-glycan M [endoplasmic reticulum membrane]
(R-COV-9683588)
nascent M [endoplasmic reticulum lumen]
(R-COV-9683586)
N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9684206)
M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9684213)
M [endocytic vesicle membrane]
(R-COV-9686687)
N-glycan M [endocytic vesicle membrane]
(R-COV-9686698)
M [virion membrane]
(R-COV-9678151)
N-glycan M [virion membrane]
(R-COV-9685474)
0.573
2
UniProt:Q96S66 CLCC1
0.527
2
UniProt:P0C6X7-PRO_0000037310 REP
0.508
2
UniProt:P33724
5
CAV1 [endocytic vesicle membrane]
(R-CFA-535009)
CAV1 [lipid droplet]
(R-CFA-163510)
CAV1 [early endosome membrane]
(R-CFA-5368451)
CAV1 [plasma membrane]
(R-CFA-534994)
CAV1 [Golgi membrane]
(R-CFA-204504)
0.505
5
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