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8b [cytosol]
Stable Identifier
R-COV-9678168
Type
Protein [EntityWithAccessionedSequence]
Species
Human SARS coronavirus
Compartment
cytosol
Synonyms
Non-structural protein 8b
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 8b binds NLRP3 (Homo sapiens)
8b:NLRP3 [cytosol] (Homo sapiens)
8b [cytosol] (Human SARS coronavirus)
8b [cytosol] (Human SARS coronavirus)
SARS-CoV-1 8b binds to IRF3 (Homo sapiens)
IRF3:8b [cytosol] (Homo sapiens)
8b [cytosol] (Human SARS coronavirus)
8b [cytosol] (Human SARS coronavirus)
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
8b binds MAP1LC3B (Homo sapiens)
8b:MAP1LC3B [cytosol] (Homo sapiens)
8b [cytosol] (Human SARS coronavirus)
8b [cytosol] (Human SARS coronavirus)
Enhanced autophagosome formation (Homo sapiens)
8b [cytosol] (Human SARS coronavirus)
External Reference Information
External Reference
UniProt:Q80H93 8b
Gene Names
8b
Chain
chain:1-84
Reference Genes
UCSC:Q80H93 8b
Participates
as a component of
IRF3:8b [cytosol] (Homo sapiens)
8b:NLRP3 [cytosol] (Homo sapiens)
8b:MAP1LC3B [cytosol] (Homo sapiens)
as an input of
SARS-CoV-1 8b binds to IRF3 (Homo sapiens)
SARS-CoV-1 8b binds NLRP3 (Homo sapiens)
8b binds MAP1LC3B (Homo sapiens)
This entity regulates
Positively
Enhanced autophagosome formation
(Homo sapiens)
Disease
Name
Identifier
Synonyms
severe acute respiratory syndrome
DOID:2945
SARS-CoV infection, SARS
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q10713 PMPCA
1
PMPCA [mitochondrial matrix]
(R-HSA-1299450)
0.527
2
UniProt:O75439 PMPCB
1
PMPCB [mitochondrial matrix]
(R-HSA-1299434)
0.527
2
UniProt:Q5JRX3 PITRM1
1
PITRM1 [mitochondrial matrix]
(R-HSA-8986159)
0.527
2
UniProt:Q96P20 NLRP3
2
NLRP3 [cytosol]
(R-HSA-561189)
K63polyUb-NLRP3 [cytosol]
(R-HSA-6783288)
0.463
7
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