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Cell surface:C4b [plasma membrane]
Stable Identifier
R-CFA-981716
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Complement cascade (Canis familiaris)
Activation of C3 and C5 (Canis familiaris)
Activation of C5 (Canis familiaris)
C5 convertases [plasma membrane] (Canis familiaris)
C4b:C2a:C3b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cleavage of C3 by C3 convertases (Canis familiaris)
C3 convertases [plasma membrane] (Canis familiaris)
C4b:C2a:C3b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Formation of classic pathway C5 convertase (Canis familiaris)
C4b:C2a:C3b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Initial triggering of complement (Canis familiaris)
C4b binds to cell surface (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Formation of Classical C3 convertase (C4b:C2a complex) (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Regulation of Complement cascade (Canis familiaris)
C3 convertases spontaneously dissociate (Canis familiaris)
C3 convertases [plasma membrane] (Canis familiaris)
C4b:C2a:C3b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CD46 binds C4b (Canis familiaris)
CD46:Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CD55 (DAF) binds C3bBb, C4bC2a (Canis familiaris)
C4bC2a, C3bBb [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CD55:C3 convertase complexes [plasma membrane] (Canis familiaris)
CD55:C4bC2a [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Canis familiaris)
CD55:C3 convertase complexes [plasma membrane] (Canis familiaris)
CD55:C4bC2a [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CD55:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1 binds C3bBb/C4bC2a (Canis familiaris)
C4bC2a, C3bBb [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1:C3bBb, C4bC2a complexes [plasma membrane] (Canis familiaris)
CR1:C4bC2a [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Complement factor I binds to MCP, CR1:C4b, C3b (Canis familiaris)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Canis familiaris)
CD46:Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Canis familiaris)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Canis familiaris)
CD46:Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Displacement of C2a/Bb by CR1 (Canis familiaris)
CR1:C3bBb, C4bC2a complexes [plasma membrane] (Canis familiaris)
CR1:C4bC2a [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
Factor I inactivates MCP/CR1-bound C4b/C3b (Canis familiaris)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Canis familiaris)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Canis familiaris)
CD46:Cell surface:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
C4b [extracellular region]
(Canis familiaris)
Cell surface [plasma membrane]
Participates
as an output of
C3 convertases spontaneously dissociate (Canis familiaris)
C4b binds to cell surface (Canis familiaris)
as an input of
CD46 binds C4b (Canis familiaris)
Formation of Classical C3 convertase (C4b:C2a complex) (Canis familiaris)
as a component of
CD55:C4b [plasma membrane] (Canis familiaris)
CD46:Cell surface:C4b [plasma membrane] (Canis familiaris)
CR1:C4b [plasma membrane] (Canis familiaris)
Cell surface:C4b:C2a [plasma membrane] (Canis familiaris)
Inferred From
Cell surface:C4b [plasma membrane]
(Homo sapiens)
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