Reactome | CFI [extracellular region]

CFI [extracellular region]

Stable Identifier

R-CFA-976749

Type

Complex

Species

Canis familiaris

Compartment

extracellular region

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

CFI [extracellular region] (Canis familiaris)
CFI [extracellular region] (Canis familiaris)

Participates

as an output of

Factor I inactivates plasma Factor H-bound C3b (Canis familiaris)
Factor I inactivates MCP/CR1-bound C4b/C3b (Canis familiaris)
Complement factor I complex formation (Canis familiaris)

as an input of

Complement factor I binds to extracellular Factor H:C3b (Canis familiaris)
Complement factor I binds to MCP, CR1:C4b, C3b (Canis familiaris)
Complement factor I binds to membrane-associated Factor H:C3b (Canis familiaris)

as a component of

CFI:CFH:C3b [extracellular region] (Canis familiaris)
CFI:CFH,FHR3:iC3b [plasma membrane] (Canis familiaris)
C4b-binding protein:Factor I [plasma membrane] (Canis familiaris)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Canis familiaris)
CFI:CFH,FHR3:C3b [plasma membrane] (Canis familiaris)

Inferred From

CFI [extracellular region] (Homo sapiens)

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