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DTL [nucleoplasm]
Stable Identifier
R-CFA-975985
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
DTL, A0A8I3MKQ1
Locations in the PathwayBrowser
Expand all
DNA Repair (Canis familiaris)
DNA Damage Bypass (Canis familiaris)
Recognition of DNA damage by PCNA-containing replication complex (Canis familiaris)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Neddylation (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Canis familiaris)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Canis familiaris)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
DTL [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3MKQ1
Gene Names
DTL
Reference Genes
BioGPS Gene:490279 DTL
ENSEMBL:ENSCAFG00845003601.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845003601.1 DTL
KEGG Gene (Canis lupus familiaris):490279 DTL
Monarch:490279 DTL
NCBI Gene:490279 DTL
Reference Transcript
RefSeq:XM_014115080.1 DTL
RefSeq:XM_014115081.1 DTL
Other Identifiers
490279
CfaAffx.19067.1.S1_s_at
GO:0000209
GO:0000278
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006281
GO:0006511
GO:0006513
GO:0006974
GO:0007095
GO:0009411
GO:0010971
GO:0016740
GO:0019985
GO:0023052
GO:0030163
GO:0031464
GO:0031465
GO:0036211
GO:0043226
GO:0045732
GO:0051726
GO:0080008
GO:0140096
Participates
as a member of
DCAF protein [nucleoplasm] (Canis familiaris)
as a component of
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Canis familiaris)
Inferred From
DTL [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_013970555.1
,
XP_013970556.1
OpenTargets
ENSG00000143476
Ensembl
ENSCAFT00845006428
,
ENSCAFP00845005112
,
ENSCAFG00845003601
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