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p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm]
Stable Identifier
R-CFA-9754133
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1 Phase (Canis familiaris)
Cyclin D associated events in G1 (Canis familiaris)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Canis familiaris)
p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Canis familiaris)
Drug-mediated inhibition of CDK4/CDK6 activity (Canis familiaris)
CDK4 inhibitors bind CDK4 (Canis familiaris)
p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Canis familiaris)
Participants
members
p-T172-CDK4:CCND1:CDK4 inhibitors (CCND1) [nucleoplasm]
(Canis familiaris)
p-T172-CDK4:CCND2:CDK4 inhibitors (CCND2) [nucleoplasm]
(Canis familiaris)
p-T172-CDK4:CCND3:CDK4 inhibitors (CCND3) [nucleoplasm]
(Canis familiaris)
Participates
as an output of
CDK4 inhibitors bind CDK4 (Canis familiaris)
This entity regulates
Negatively
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes
(Canis familiaris)
Inferred From
p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm]
(Homo sapiens)
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