Reactome | KCNJ10 [plasma membrane]

KCNJ10 [plasma membrane]

Stable Identifier

R-CFA-975290

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

KCNJ10, A0A8I3Q5Q2

Locations in the PathwayBrowser

Expand all

Neuronal System (Canis familiaris)

- Potassium Channels (Canis familiaris)
  - Inwardly rectifying K+ channels (Canis familiaris)
    - G protein gated Potassium channels (Canis familiaris)
      - Activation of G protein gated Potassium channels (Canis familiaris)
        
        Activation of GIRK/Kir3 Channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
    - Potassium transport channels (Canis familiaris)
      - Activation of Potassium transport channels (Canis familiaris)
        
        Potassium transport channels (Kir 1.1 and Kir 4.1/5.1) [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
- Transmission across Chemical Synapses (Canis familiaris)
  - Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
    - GABA receptor activation (Canis familiaris)
      - GABA B receptor activation (Canis familiaris)
        
        Activation of GABAB receptors (Canis familiaris)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Canis familiaris)
        
        Activation of GIRK/Kir3 Channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Canis familiaris)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ10 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3Q5Q2

Gene Names

KCNJ10

Reference Genes

ENSEMBL:ENSCAFG00845030876.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845030876.1 KCNJ10

Other Identifiers

488635

Cfa.9020.2.A1_a_at

CfaAffx.18445.1.S1_at

GO:0005215

GO:0005242

GO:0006811

GO:0006813

GO:0016020

GO:0034220

GO:0034702

GO:0055085

GO:0071805

GO:0098655

Participates

as a component of

Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)

as a member of

Kirx.x that interacts with Kir2.1 [plasma membrane] (Canis familiaris)

Inferred From

KCNJ10 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000177807

Ensembl

ENSCAFG00845030876, ENSCAFP00845043154, ENSCAFT00845054874

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