Reactome | p-Pellino:hp-IRAK1:TRAF6 [endosome membrane]

p-Pellino:hp-IRAK1:TRAF6 [endosome membrane]

Stable Identifier

R-CFA-975166

Type

Complex

Species

Canis familiaris

Compartment

endosome membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
TRAF6:hp-IRAK1 [endosome membrane] (Canis familiaris)

Participates

as an input of

Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)

as an output of

IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Canis familiaris)

Inferred From

TRAF6:hp-IRAK1:Pellino [endosome membrane] (Homo sapiens)

p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Homo sapiens)

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