Reactome | COA1 [mitochondrial inner membrane]

COA1 [mitochondrial inner membrane]

Stable Identifier

R-CFA-9708001

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial inner membrane

Synonyms

COA1, A0A8I3NJZ3

Locations in the PathwayBrowser

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Metabolism (Canis familiaris)

- Aerobic respiration and respiratory electron transport (Canis familiaris)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Canis familiaris)
    - Respiratory electron transport (Canis familiaris)
      - Complex I biogenesis (Canis familiaris)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        370 kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        COA1:MT-ND2 [mitochondrial inner membrane] (Canis familiaris)
        
        COA1 [mitochondrial inner membrane] (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        370 kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        COA1:MT-ND2 [mitochondrial inner membrane] (Canis familiaris)
        
        COA1 [mitochondrial inner membrane] (Canis familiaris)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        370 kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        COA1:MT-ND2 [mitochondrial inner membrane] (Canis familiaris)
        
        COA1 [mitochondrial inner membrane] (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        370 kDa subcomplex (-MCIA complex) [mitochondrial inner membrane] (Canis familiaris)
        
        COA1:MT-ND2 [mitochondrial inner membrane] (Canis familiaris)
        
        COA1 [mitochondrial inner membrane] (Canis familiaris)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        370 kDa subcomplex (-MCIA complex) [mitochondrial inner membrane] (Canis familiaris)
        
        COA1:MT-ND2 [mitochondrial inner membrane] (Canis familiaris)
        
        COA1 [mitochondrial inner membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NJZ3

Gene Names

COA1

Reference Genes

ENSEMBL:ENSCAFG00845011827.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845011827.1 COA1

Other Identifiers

608597

CfaAffx.6161.1.S1_at

Participates

as a component of

COA1:MT-ND2 [mitochondrial inner membrane] (Canis familiaris)

Inferred From

COA1 [mitochondrial inner membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000106603

Ensembl

ENSCAFG00845011827, ENSCAFP00845016504, ENSCAFT00845020999