Reactome | HRAS [plasma membrane]

HRAS [plasma membrane]

Stable Identifier

R-CFA-9665052

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

S-Farn-Me HRAS, J9P550

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- MAPK family signaling cascades (Canis familiaris)
  - MAPK1/MAPK3 signaling (Canis familiaris)
    - RAF/MAP kinase cascade (Canis familiaris)
      - RAS processing (Canis familiaris)
        
        RAS proteins are depalmitoylated (Canis familiaris)
        
        S-Farn-Me KRAS4A, HRAS, NRAS [plasma membrane] (Canis familiaris)
        
        HRAS [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9P550

Gene Names

HRAS

Reference Genes

BioGPS Gene:403735 HRAS

ENSEMBL:ENSCAFG00000031029

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000031029 HRAS

KEGG Gene (Canis lupus familiaris):403735 HRAS

Monarch:403735 HRAS

NCBI Gene:403735 HRAS

Reference Transcript

RefSeq:NM_001287069.1 HRAS

Other Identifiers

403735

Cfa.3599.1.S1_s_at

CfaAffx.10735.1.S1_at

GO:0000166

GO:0001934

GO:0002376

GO:0003674

GO:0003924

GO:0005525

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005794

GO:0005829

GO:0005886

GO:0006464

GO:0006605

GO:0006810

GO:0006897

GO:0006950

GO:0007010

GO:0007049

GO:0007050

GO:0007165

GO:0007264

GO:0007265

GO:0007267

GO:0007568

GO:0007569

GO:0008022

GO:0008150

GO:0008219

GO:0008283

GO:0008284

GO:0008285

GO:0009058

GO:0010628

GO:0010629

GO:0010863

GO:0015031

GO:0016020

GO:0016192

GO:0019003

GO:0022607

GO:0030335

GO:0032729

GO:0034260

GO:0034641

GO:0040011

GO:0042088

GO:0042832

GO:0043167

GO:0043226

GO:0043406

GO:0043410

GO:0043524

GO:0043547

GO:0045944

GO:0046330

GO:0048169

GO:0048870

GO:0050679

GO:0050852

GO:0070374

GO:0071480

GO:0090303

GO:0090314

GO:0090398

GO:0097193

GO:0098696

GO:0098978

GO:1900029

GO:2000251

GO:2000630

Participates

as a member of

S-Farn-Me KRAS4A, HRAS, NRAS [plasma membrane] (Canis familiaris)

Other forms of this molecule

HRAS [plasma membrane]

HRAS [Golgi membrane]

HRAS [endoplasmic reticulum membrane]

HRAS [cytosol]

HRAS [plasma membrane]

Inferred From

S-Farn-Me HRAS [plasma membrane] (Homo sapiens)

Modified Residues

Name

S-farnesyl-L-cysteine methyl ester at 186 (in Homo sapiens)

Coordinate

186

PsiMod Name

S-farnesyl-L-cysteine methyl ester

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine methyl ester.

Cross References

RefSeq

NP_001273998.1

OpenTargets

ENSG00000174775

Ensembl

ENSCAFG00000031029, ENSCAFT00000048281, ENSCAFP00000040726

VGNC

56090

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